Modified versus classic Nuss repair for pectus excavatum in adolescents
Official title: Single-Center Retrospective Comparative Analysis Of Modified Vs. Classical Nuss Technique In The Surgical Correction Of Pectus Excavatum "
Run by University Hospital, Strasbourg, France · NCT07312448 · Data updated 2026-11-12
This research will see if the modified or classic Nuss procedure gives shorter surgery time, less postoperative pain, shorter ICU stays, and better cosmetic results for teens with pectus excavatum.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 11 Years to 18 Years |
| Sex | All |
| Enrollment | 80 (estimated) |
| Sponsor | University Hospital, Strasbourg, France Academic / other |
| Locations | 1 site (Strasbourg) |
| Status | Recruiting |
| Started | December 2, 2024 |
| Main results expected | February 2026 |
| Study ends | February 2026 |
| Registry record updated | December 31, 2025 |
| Trial ID | NCT07312448 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adolescents aged 11–18 with pectus excavatum and a Haller index ≥2.25 who underwent either the classic or modified Nuss procedure between 2010 and 2024.
✕Probably not a fit
Patients younger than 11 or older than 19, those with a Haller index below 2.25, or those treated with Ravitch or other non-Nuss techniques will not be included and are unlikely to benefit from the study's findings.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This is a retrospective observational comparison of adolescents (11–18 years) who underwent either the classic or modified Nuss repair at CHU de Strasbourg between 2010 and 2024. Eligible patients have a Haller index of 2.25 or higher and data will be collected from surgical records, pain scores, ICU stay documentation, and follow-up cosmetic assessments. The study will compare operative time, postoperative pain control, length of ICU stay, complications, and cosmetic outcomes between the two technique groups using standard statistical methods. Findings aim to highlight any technique-related differences that could inform surgical practice for pectus excavatum.
Why it matters
Potential benefit: If one approach shows clear advantages, patients could receive the technique associated with shorter operations, less pain, and improved cosmetic results.
How similar studies have gone: There are surgical series reporting outcomes for Nuss variations, but direct head-to-head comparative data between classic and modified techniques remain limited.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients aged 11 to 18 years. * Patients who underwent surgery between 2010 and 2024 using either the classic or modified Nuss technique. - Patient with a Haller index of 2.25 or higher. Exclusion Criteria: * Patients with a Haller score below 2.25. * Patients who have undergone surgery using alternative techniques such as Ravitch or modified Ravitch. * Patients under 11 years of age or over 19 years of age.
Where it's running
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Service de Chirurgie Pédiatrique - Réanimation - CHU de Strasbourg - France
Strasbourg, France Recruiting
Study contacts
- Study coordinator: Isabelle TALON, MD, PhD
- Email: Isabelle.TALON@chru-strasbourg.fr
- Phone: 33 3 88 12 72 96
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This study is testing whether using cryoanalgesia for one minute instead of two minutes can help reduce pain after Nuss surgery for people with pectus excavatum.
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.