Modified periosteal inhibition for immediate dental implants in the aesthetic zone

Modified Periosteal Inhibition Utilizing Bone Graft Versus Collagen Sponge with Simultaneous Implant Placement in Aesthetic Zone

Phase1; Phase2 Interventional Tanta University · NCT06519773

This study is testing a new method for placing immediate dental implants in the front of the mouth to see if it helps keep the surrounding bone intact and improves the look of the implants.

Quick facts

PhasePhase1; Phase2
Study typeInterventional
Enrollment20 (estimated)
Ages18 Years to 60 Years
SexAll
SponsorTanta University Academic / other
Drugs / interventionschemotherapy
Locations1 site (Tanta)
Trial IDNCT06519773 on ClinicalTrials.gov

What this trial studies

This clinical trial investigates the effectiveness of modified periosteal inhibition during the placement of immediate dental implants in the maxillary anterior region. It involves a randomized controlled design with twenty surgical sites divided into two groups, where patients undergo phase I therapy followed by a traumatic extraction of non-restorable teeth. The study utilizes cone beam computed tomography for pre-extraction measurements and aims to preserve the labial plate of bone during the extraction process. The surgical technique includes careful implant placement guided by a prefabricated template to optimize aesthetic outcomes.

Who should consider this trial

Good fit: Ideal candidates are individuals with non-restorable teeth in the maxillary anterior region who have an intact labial plate of bone and meet specific periodontal criteria.

Not a fit: Patients with systemic conditions, pregnant or lactating women, smokers, or those with a compromised buccal plate of bone may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could enhance the success rate of immediate dental implants and improve aesthetic results for patients.

How similar studies have performed: While similar approaches have been explored, this specific methodology of modified periosteal inhibition in immediate implant placement is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Intact labial plate of bone with thickness ≤1 mm (Socket type I).
2. Moderate to thick gingival phenotype.
3. Bone quality ranges from D2-D3 as gained from preoperative cone beam computed tomography.
4. Presence of at least 3 mm of keratinized gingiva.
5. Optimal compliance as evidenced by no missing treatment appointments and positive attitude towards oral hygiene.

Exclusion Criteria:

1. Medically compromised patients and systemic conditions precluding implant and periodontal surgery.
2. Pregnant or lactating women.
3. Smoking
4. Absence of buccal plate of bone.
5. History of chemotherapy, radiotherapy in head and/or neck region.
6. Bisphosphonate therapy.

Where this trial is running

Tanta

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Immediate Dental ImplantImmediate implantModified periosteal inhibition
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.