Modified constraint-induced movement therapy with or without proprioceptive neuromuscular facilitation for children after stroke

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized trial will enroll 20 children with pediatric stroke and upper-extremity impairments, randomly assigning them to six weeks of modified constraint-induced movement therapy (CIMT) alone or CIMT combined with proprioceptive neuromuscular facilitation (PNF). Therapists will deliver the interventions and participants will be evaluated before and after the intervention using standardized measures including the Pediatric Motor Activity Log (PMAL), Modified Ashworth Scale (MAS), and Manual Ability Classification System (MACS), along with measures of muscle tone and physical activity. Data will be entered and analyzed in SPSS v26.0 to compare changes between the two groups. The protocol excludes children with epilepsy, recent botulinum toxin injections, cognitive impairment, recent fractures, or recent upper-extremity surgery.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Paeds Patients with confirmed diagnosis of Stroke
* Children between age 5 to 13 years
* Modified Ashworth Scale spasticity level 1 and 2.
* Patients having Manual Ability Classification System Score between 3 to 6.
* GMFCS level 1 and 2
* Patient having in affected upper extremity at least 20◦ of active wrist extension starting from the full flexion, 10◦ of active extension or abduction in the thumb, and 10◦ of active extension in the metacarpophalangeal and interphalangeal joints of the other fingers

Exclusion Criteria:

* Patients with epilepsy or seizure disorder
* Patients with history of botulinum toxin injection, cognitive impairment, fracture and any surgical procedure in upper extremity

Where it's running

• Imran Amjad
  Lahore, Punjab Province, Pakistan Recruiting

Study contacts

• Principal investigator: Maida Shabbir, MS-PT — Riphah International University
• Study coordinator: IMRAN AMJAD, PhD
• Email: imran.amjad@riphah.edu.pk
• Phone: 9233224390125

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.