Modified anterior palatoplasty for obstructive sleep apnea

Barbed Suture Modified Anterior Palatoplasty In Management of Mild and Moderate Obstructive Sleep Apnea Syndrome

Not applicable Interventional Benha University · NCT04572503

This study tests a new surgical technique to see if it can help people with mild to moderate obstructive sleep apnea sleep better after the procedure.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment20 (estimated)
Ages18 Years and up
SexAll
SponsorBenha University Academic / other
Locations1 site (Banhā, Qalyubia Governorate)
Trial IDNCT04572503 on ClinicalTrials.gov

What this trial studies

This study evaluates the effectiveness of a modified surgical technique called barbed suture anterior palatoplasty in treating patients with mild to moderate obstructive sleep apnea syndrome (OSAS). A total of 20 patients will undergo this procedure, which involves general anesthesia and bilateral tonsillectomy, followed by specific surgical steps to modify the soft palate. The aim is to assess improvements in sleep apnea symptoms and overall patient outcomes post-surgery.

Who should consider this trial

Good fit: Ideal candidates for this study are patients diagnosed with mild to moderate obstructive sleep apnea syndrome who have retropalatal collapses and are noncompliant with CPAP.

Not a fit: Patients with severe obstructive sleep apnea, significant craniofacial anomalies, or those unfit for general anesthesia may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could provide a new surgical option for patients with mild to moderate obstructive sleep apnea who are noncompliant with CPAP therapy.

How similar studies have performed: While this specific modification may be novel, similar surgical approaches have shown promise in treating obstructive sleep apnea.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients with mild to moderate obstructive sleep apnea syndrome.
* Patients diagnosed with mild (AHI 5 to15) and moderate (AHI 16 to 30) OSAS with only retropalatal collapses
* Patients who are noncompliant with Continuous positive airway pressure (CPAP).

Exclusion Criteria:

* Patients diagnosed with sever OSAS (AHI more than 30)
* The main site of obstruction at retrolingual level or multilevel obstruction.
* Contraindication of surgery (e.g. cardiovascular problems and bleeding tendency).
* Patients with significant craniofacial anomalies affecting airway.
* Patients with BMI\>40 kg/m2.
* Patients unfit for general anesthesia.
* History of previous velopharyngeal or lingual surgeries.

Where this trial is running

Banhā, Qalyubia Governorate

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Obstructive Sleep ApneaBarbed sutureAnterior palatoplasty
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.