Modeling outcomes in patients with acquired brain injuries

Modeling Trajectories of Functional Outcome in Patients With Severe Acquired Brain Injuries Using a Non-Linear Dynamic Evolution Approach.

Observational Istituto per la Ricerca e l'Innovazione Biomedica · NCT06162091

This study is testing how artificial intelligence can help predict recovery for people with acquired brain injuries to improve their rehabilitation.

Quick facts

Study typeObservational
Enrollment190 (estimated)
Ages18 Years and up
SexAll
SponsorIstituto per la Ricerca e l'Innovazione Biomedica Academic / other
Locations1 site (Messina)
Trial IDNCT06162091 on ClinicalTrials.gov

What this trial studies

This observational study focuses on patients with acquired brain injuries (ABI) to predict recovery trajectories using artificial intelligence algorithms. By analyzing various demographic, clinical, and psychosocial factors, the study aims to improve the understanding of recovery patterns and enhance rehabilitation strategies. Data will be collected from patients diagnosed with severe ABI within three months of the injury, allowing for a comprehensive assessment of recovery potential. The goal is to provide clinicians with better predictive tools for patient outcomes.

Who should consider this trial

Good fit: Ideal candidates include adults aged 18 and older who have been diagnosed with severe acquired brain injuries within three months of the event.

Not a fit: Patients with pre-existing disabling neurological or orthopedic conditions and psychiatric disorders may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to more personalized and effective rehabilitation strategies for patients with acquired brain injuries.

How similar studies have performed: Other studies utilizing artificial intelligence for predicting outcomes in brain injuries have shown promise, indicating that this approach may yield valuable insights.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* patients with clinical diagnosis of severe acquired brain injury of different etiology (traumatic, hemorrhagic vascular,ischemic vascular, anoxic, infectious, other etiology
* interval since the acute occurrence that led to the clinical condition of ≤3 months duration
* age of 18 years or older
* informed consent signed by family member/caregiver/supporting caregiver

Exclusion Criteria:

* Positive remote medical history of pre-existing disabling neurological or orthopedic conditions and psychiatric disorders

Where this trial is running

Messina

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Brain Injuriesacquired brain injuryfunctional outcomeModeling trajectoriesmathematical models
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.