Model for diagnosing uterine sarcoma and myoma using radiomic features
Construction of a Model for the Differential Diagnosis of SArcoma/myoma Based on the RAdiomics Features: Single-center Observational Study
This study is testing a new way to tell the difference between aggressive uterine sarcomas and benign myomas using special features from CT scans before surgery.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 176 (estimated) |
| Ages | 18 Years to 80 Years |
| Sex | Female |
| Sponsor | IRCCS Azienda Ospedaliero-Universitaria di Bologna Academic / other |
| Locations | 1 site (Bologna, Bologna) |
| Trial ID | NCT06805019 on ClinicalTrials.gov |
What this trial studies
This observational study aims to develop a model for the differential diagnosis of uterine sarcoma and myoma based on radiomic features obtained from pre-operative CT scans. Uterine sarcomas are aggressive tumors with a high risk of recurrence, while uterine myomas are common benign growths. The study will analyze imaging data to improve diagnostic accuracy before surgical intervention, potentially leading to better treatment planning. Patients will be included based on specific histological diagnoses and imaging criteria.
Who should consider this trial
Good fit: Ideal candidates are women aged 18 to 80 with a histological diagnosis of uterine sarcoma or myoma and recent pre-operative CT scans.
Not a fit: Patients with low-quality CT images or those with other active neoplasms diagnosed within the last five years may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance the accuracy of pre-operative diagnoses, leading to more tailored and effective treatment strategies for patients.
How similar studies have performed: While the approach of using radiomic features for diagnosis is gaining traction, this specific application for differentiating uterine sarcoma from myoma is relatively novel and not extensively tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Histological diagnosis of uterine sarcoma or myoma * Patients with pre-operative CT performed for diagnostic suspicion no more than 30 days before surgery * Age between 18 and 80 years * Patients followed in the clinical care path in our center * Obtaining informed consent Exclusion Criteria: * Low quality of CT images. * Patients affected by other active neoplasms or diagnosed less than 5 years before the diagnosis of uterine sarcoma or myoma.
Where this trial is running
Bologna, Bologna
- IRCCS Azienda Ospedaliero-Universitaria — Bologna, Bologna, Italy (Recruiting)
Study contacts
- Study coordinator: Anna Myriam Perrone, MD
- Email: myriam.perrone@unibo.it
- Phone: 051 2144368
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.