Mobile patient health technology to increase lung cancer screening in high‑risk adults

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This pragmatic, randomized controlled trial will embed an electronic outreach intervention (mPATH‑Lung) within an academic learning health system and randomize eligible patients to one of four outreach approaches: portal message only, portal message plus reminder texts, text message plus reminders, or usual care. The design intentionally enrolls fully powered cohorts of racial/ethnic minorities and rural residents to compare effectiveness across vulnerable subgroups. The primary outcome is uptake of lung cancer screening, with secondary aims to compare outreach strategies, estimate revenue from increased screening and downstream care, and evaluate potential over‑screening using HEDIS‑based exclusion criteria. The intervention is delivered via existing patient portal accounts or SMS and is restricted to patients established with the Wake Forest health network who have a North Carolina address.

Why it matters

Who can join: the full rules

Inclusion Criteria:

Eligible patients will:

* Meet the Medicare criteria for lung cancer screening, as updated in February 2022:
* Age 50 - 77 years
* Smoked at least 20 pack years
* Current smoker or quit smoking within the past 15 years
* Be established with a primary care provider within the Atrium Health Wake Forest Baptist health network (defined as having completed at least 1 primary care appointment in the past 6 months or have completed at least 2 primary care appointments within the past 18 months or being scheduled to see a health network primary care provider within the next 30 days).
* Have a patient portal account or cellphone number listed in the electronic health record
* Have a North Carolina address listed in the electronic health record

Exclusion Criteria:

The following patients will be excluded:

* Patients flagged as needing a language interpreter in the electronic health record for any language other than Spanish (electronic messages and intervention are deliverable in English or Spanish only)
* Those for whom lung cancer screening would be or may be inappropriate:

electronic health record Prior history of lung cancer electronic health record Chest CT within the last 12 months electronic health record Those meeting the HEDIS COL-E measure exclusion criteria based on significant comorbidities and/or frailty.

Where it's running

• Atrium Health Wake Forest Baptist
  Winston-Salem, North Carolina, United States Recruiting

Study contacts

• Principal investigator: Brent Heideman, Jr., MD — Wake Forest Baptist Comprehensive Cancer Center
• Study coordinator: Study Coordinator
• Email: Aliza.randazzo@advocatehealth.org
• Phone: 704-355-2000

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.