Mobile low-dose CT lung cancer screening program

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

MobILYAD compares a demedicalized CT-equipped mobile van staffed by trained nurses with a conventional hospital-based screening pathway at Hôpital Lyon Sud to determine which better reaches socially disadvantaged populations. Eligible participants receive low-dose chest CT, spirometry, a cardiovascular risk check, smoking cessation support, and optional biospecimen collection. The project uses a proactive 'reach-out' strategy informed by mobile screening models from other countries and by mobile mammography experience in France. Results will inform the national pilot program (IMPULSION) planned for 2025 by measuring participation, detection rates, and operational feasibility.

Why it matters

Who can join: the full rules

Inclusion Criteria \* :

* Persons aged over 50 and under 75 (74 years of age or older).
* Active smokers or former smokers who quit less than 15 years ago.
* Persons whose consumption is estimated at 20 packs/year or more, down to ≥15 cigarettes/day for a duration of consumption of ≥25 years and up to ≥10 cigarettes/day for ≥30 years, which takes into account the predominance of duration of consumption over quantity consumed in the risk of lung cancer. A pack-year corresponds to the consumption of one pack of 20 manufactured cigarettes per day for one year. A multiplier coefficient will be taken into account depending on the mode of consumption: Rolled cigarettes: 2; Cigarillos: 3; Cigars: 4; Pipes: 2.5; Hookahs: 25.
* Persons affiliated with social security. - Person having signed their consent to participate in the study after having received full information about it, including the risks associated with participation.

  * Exclusion Criteria \* :
* Individuals with severe comorbidities contraindicating lung cancer investigations and/or treatment (including surgery or stereotactic radiotherapy);
* Individuals with impaired general condition (PS 2 and above);
* Individuals with dyspnea at rest (mMRC4);
* Individuals with a history of cancer undergoing active surveillance by chest computed tomography (CT or PET scan); personal history of lung cancer (lifetime);
* Individuals with symptoms suggestive of lung cancer (hemoptysis, unexplained weight loss, recent onset or change in respiratory symptoms, etc.);
* Individuals refusing to participate in the study
* Individuals withdrawing their consent.

Where it's running

• " Centre de dépistage mobile " - Hôpital Lyon Sud
  Pierre-Bénite, France Recruiting
• Service de Pneumologie " Centre de dépistage non mobile " - Hôpital Lyon Sud
  Pierre-Bénite, France Recruiting

Study contacts

• Study coordinator: Sébastien COURAUD, Pr
• Email: sebastien.couraud@chu-lyon.fr
• Phone: 04 78 86 44 01

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.