Mobile lifestyle app to prevent heart disease in high-risk urban office workers in Karachi
Official title: m-Lifestyle Intervention for Employees (m-LIfE): Protocol for a Pilot Cluster Randomized Controlled Trial on Cardiovascular Disease Prevention Strategies
Run by Aga Khan University · NCT06981247 · Data updated 2026-11-12
A mobile app called m-LIfE is being tested to see if it helps sedentary bank employees in Karachi eat healthier and move more over 12 weeks.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 20 Years to 65 Years |
| Sex | All |
| Enrollment | 84 (estimated) |
| Sponsor | Aga Khan University Academic / other |
| Locations | 1 site (Karachi, Sindh) |
| Status | Recruiting |
| Started | June 22, 2026 |
| Main results expected | October 2026 |
| Study ends | November 2026 |
| Registry record updated | August 12, 2026 |
| Trial ID | NCT06981247 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are bank employees in urban Karachi with at least 6 months of tenure and no history of major cardiovascular events.
✕Probably not a fit
Individuals with recent myocardial infarction or stroke, pregnant women, or those unable to engage in physical activity may not benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This interventional study tests a context-specific mHealth app, m-LIfE, aimed at increasing physical activity and improving diet among high-risk urban office workers in Karachi. Participants are bank employees with at least 6 months of experience, randomized to use the app for 12 weeks or receive routine printed prevention materials. The app provides reminders and tips to take breaks, exercise, and choose healthier foods. The trial will assess changes in lifestyle behaviors related to cardiovascular risk factors in a real-world workplace setting. Primary care and cardiology stakeholders in Pakistan collaborate with Aga Khan University and the Fogarty Center to explore scalable prevention strategies in LMICs.
Why it matters
Potential benefit: If successful, the app could help reduce cardiovascular risk by promoting more movement and healthier eating among office workers.
How similar studies have gone: Prior digital lifestyle interventions have shown promise in reducing risk factors, though context-specific implementation in LMIC urban workplaces is still being explored.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: • At least 6 months of job experience in any bank Exclusion Criteria: * Diagnosed case of myocardial infarction, stroke, coronary heart disease, cerebrovascular disease, or peripheral arterial diseases * Pregnant women * Individuals with acute illnesses that limit physical activity
Where it's running
-
Aga Khan University
Karachi, Sindh, Pakistan Recruiting
Study contacts
- Principal investigator: Aysha Almas, PhD — Aga Khan University
- Study coordinator: Samina Akhtar
- Email: samina.yousanaf@aku.edu
- Phone: +923314312920
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.