Clinical trial Recruiting at 1 site Interventional Ages 20 to 65

Mobile lifestyle app to prevent heart disease in high-risk urban office workers in Karachi

Official title: m-Lifestyle Intervention for Employees (m-LIfE): Protocol for a Pilot Cluster Randomized Controlled Trial on Cardiovascular Disease Prevention Strategies

Run by Aga Khan University · NCT06981247 · Data updated 2026-11-12

A mobile app called m-LIfE is being tested to see if it helps sedentary bank employees in Karachi eat healthier and move more over 12 weeks.

More Cardiovascular Diseases trials

Quick facts

Study typeInterventional
Ages20 Years to 65 Years
SexAll
Enrollment84 (estimated)
SponsorAga Khan University
Academic / other
Locations1 site (Karachi, Sindh)
StatusRecruiting
StartedJune 22, 2026
Main results expectedOctober 2026
Study endsNovember 2026
Registry record updatedAugust 12, 2026
Trial IDNCT06981247 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are bank employees in urban Karachi with at least 6 months of tenure and no history of major cardiovascular events.

Probably not a fit

Individuals with recent myocardial infarction or stroke, pregnant women, or those unable to engage in physical activity may not benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study tests a context-specific mHealth app, m-LIfE, aimed at increasing physical activity and improving diet among high-risk urban office workers in Karachi. Participants are bank employees with at least 6 months of experience, randomized to use the app for 12 weeks or receive routine printed prevention materials. The app provides reminders and tips to take breaks, exercise, and choose healthier foods. The trial will assess changes in lifestyle behaviors related to cardiovascular risk factors in a real-world workplace setting. Primary care and cardiology stakeholders in Pakistan collaborate with Aga Khan University and the Fogarty Center to explore scalable prevention strategies in LMICs.

Why it matters

Potential benefit: If successful, the app could help reduce cardiovascular risk by promoting more movement and healthier eating among office workers.

How similar studies have gone: Prior digital lifestyle interventions have shown promise in reducing risk factors, though context-specific implementation in LMIC urban workplaces is still being explored.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

• At least 6 months of job experience in any bank

Exclusion Criteria:

* Diagnosed case of myocardial infarction, stroke, coronary heart disease, cerebrovascular disease, or peripheral arterial diseases
* Pregnant women
* Individuals with acute illnesses that limit physical activity

Where it's running

  • Aga Khan University
    Karachi, Sindh, Pakistan
    Recruiting

Study contacts

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.