Mobile intervention to reduce anger in Veterans with PTSD

A Randomized Controlled Trial of the Mobile Anger Reduction Intervention for Veterans

Not applicable Interventional VA Office of Research and Development · NCT06094933

This study is testing a new mobile program designed to help Veterans with PTSD manage their anger better compared to a regular health education program.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment150 (estimated)
SexAll
SponsorVA Office of Research and Development Federal
Locations1 site (Durham, North Carolina)
Trial IDNCT06094933 on ClinicalTrials.gov

What this trial studies

This project aims to address the common issue of anger management among combat Veterans diagnosed with posttraumatic stress disorder (PTSD). The study will compare the Mobile Anger Reduction Intervention (MARI) with a health education mobile intervention (HED) to evaluate their effectiveness in reducing anger and improving functional outcomes. Participants will be randomly assigned to either the MARI or HED condition, with the hypothesis that MARI will lead to greater reductions in anger and enhanced functionality. The intervention leverages mobile health technology to reach Veterans in need of effective anger management solutions.

Who should consider this trial

Good fit: Ideal candidates for this study are Veterans diagnosed with PTSD who also report significant issues with anger.

Not a fit: Patients currently experiencing active psychosis or severe suicidal ideation may not benefit from this study.

Why it matters

Potential benefit: If successful, this intervention could significantly improve anger management and overall quality of life for Veterans with PTSD.

How similar studies have performed: While the use of mobile health interventions is gaining traction, this specific approach targeting anger reduction in PTSD has not been widely tested, making it a novel endeavor.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Veterans diagnosed with PTSD, established via chart review and a score of greater than or equal to 33 on the PTSD Checklist for DSM-5 (PCL-5)
* Reporting a score of greater than or equal to 12 on the 5-item Dimensions of Anger Reactions Scale
* Have not had any changes to type or dose of psychiatric medications for 3 months, with no plans to make adjustments in the next 6 months
* Able to read at least 6th grade level material

Exclusion Criteria:

* Currently in a period of active psychosis or mania
* Exhibit current prominent suicidal or homicidal ideation requiring immediate intervention
* Have used the MARI application before as part of another research study
* Receiving (or plan to receive) other anger management psychotherapy or trauma-focused therapy for PTSD (i.e., prolonged exposure, cognitive processing therapy during the course of the study

Where this trial is running

Durham, North Carolina

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Posttraumatic Stress DisorderAngerposttraumatic stress disorderangerhostile interpretation biasmHealth
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.