Clinical trial Recruiting at 1 site Interventional

Mobile intervention to reduce anger in Veterans with PTSD

Official title: A Randomized Controlled Trial of the Mobile Anger Reduction Intervention for Veterans

Run by VA Office of Research and Development · NCT06094933 · Data updated 2026-11-12

This study is testing a new mobile program designed to help Veterans with PTSD manage their anger better compared to a regular health education program.

Quick facts

Study typeInterventional
SexAll
Enrollment150 (estimated)
SponsorVA Office of Research and Development
Federal
Locations1 site (Durham, North Carolina)
StatusRecruiting
StartedNovember 12, 2024
Main results expectedOctober 30, 2027
Study endsMarch 31, 2028
Registry record updatedSeptember 21, 2026
Trial IDNCT06094933 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are Veterans diagnosed with PTSD who also report significant issues with anger.

Probably not a fit

Patients currently experiencing active psychosis or severe suicidal ideation may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This project aims to address the common issue of anger management among combat Veterans diagnosed with posttraumatic stress disorder (PTSD). The study will compare the Mobile Anger Reduction Intervention (MARI) with a health education mobile intervention (HED) to evaluate their effectiveness in reducing anger and improving functional outcomes. Participants will be randomly assigned to either the MARI or HED condition, with the hypothesis that MARI will lead to greater reductions in anger and enhanced functionality. The intervention leverages mobile health technology to reach Veterans in need of effective anger management solutions.

Why it matters

Potential benefit: If successful, this intervention could significantly improve anger management and overall quality of life for Veterans with PTSD.

How similar studies have gone: While the use of mobile health interventions is gaining traction, this specific approach targeting anger reduction in PTSD has not been widely tested, making it a novel endeavor.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Veterans diagnosed with Post-traumatic stress disorder (PTSD), established via chart review and a score of greater than or equal to 33 on the PTSD Checklist for DSM-5 (PCL-5)
* Reporting a score of greater than or equal to 12 on the 5-item Dimensions of Anger Reactions Scale
* Have not had any changes to type or dose of psychiatric medications for 3 months, with no plans to make adjustments in the next 6 months
* Able to read at least 6th grade level material

Exclusion Criteria:

* Currently in a period of active psychosis or mania
* Exhibit current prominent suicidal or homicidal ideation requiring immediate intervention
* Have used the Mobile Anger Reduction Intervention (MARI) application before as part of another research study
* Receiving (or plan to receive) other anger management psychotherapy or trauma-focused therapy for PTSD (i.e., prolonged exposure, cognitive processing therapy during the course of the study

Where it's running

  • Durham VA Medical Center, Durham, NC
    Durham, North Carolina, United States
    Recruiting

Study contacts

  • Principal investigator: Kirsten H Dillon, PhD — Durham VA Medical Center, Durham, NC
  • Study coordinator: Kirsten H Dillon, PhD
  • Email: Kirsten.Dillon@va.gov
  • Phone: (919) 286-0411

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.