Mobile app to help patients with atrial fibrillation take their medication

The ReInforcement of Adherence Via Self-monitoring App Orchestrating Biosignals and Medication of RivoXaban in Patients with Atrial Fibrillation and Co-morbidities: Randomised Control Study(RIVOX-AF Study)

Not applicable Interventional Seoul National University Bundang Hospital · NCT05557123

This study tests whether a mobile app can help people with atrial fibrillation remember to take their medication on time better than standard treatment.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment1042 (estimated)
Ages19 Years and up
SexAll
SponsorSeoul National University Bundang Hospital Academic / other
Locations1 site (Seongnam)
Trial IDNCT05557123 on ClinicalTrials.gov

What this trial studies

The RIVOX-AF study is a multicenter, randomized controlled trial designed to improve medication adherence among patients with atrial fibrillation (AF) using a mobile app. Participants will be divided into two groups: one receiving feedback and reminders through the app and the other receiving conventional treatment. The app aims to enhance patient engagement and ensure timely medication intake. Eligible patients include those aged 19 and older with AF and certain comorbidities who are able to use a smartphone.

Who should consider this trial

Good fit: Ideal candidates are patients aged 19 and older with atrial fibrillation and one or more comorbidities who can use a smartphone.

Not a fit: Patients with severe renal impairment, significant mitral valve issues, or those with legal or psychiatric problems may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could significantly improve medication adherence and health outcomes for patients with atrial fibrillation.

How similar studies have performed: Other studies have shown promise in using mobile apps to improve medication adherence, suggesting this approach could be effective.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients with AF aged 19 years or older with one or more comorbidities including heart failure, myocardial infarction, stable angina, hypertension or diabetes mellitus (Patients can be enrolled 3 months after myocardial infarction or percutaneous coronary intervention).
* patients who already took or plan to take rivoxban
* patients who able to use smart phone

Exclusion Criteria:

* creatinine clearance \<15ml/min
* moderate or severe mitral stenosis
* mitral valve operation history
* current alcohol abuse or alcohol abus history
* Not eligible for study due to legal or psychiatric problem
* enrolled other clinical study within 4 weeks
* declined to enroll the study

Where this trial is running

Seongnam

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Atrial Fibrillationatrial fibrillationmobile app
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.