Mobile app to help caregivers of Alzheimer's patients

I-CARE 2 RCT: Mobile Telehealth to Reduce Alzheimer'S-related Symptoms for Caregivers and Patients

Not applicable Interventional Indiana University · NCT05733520

This study is testing a mobile app designed to help caregivers of Alzheimer's patients see if it can make their lives easier and improve the patients' symptoms over a year.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment184 (estimated)
Ages18 Years and up
SexAll
SponsorIndiana University Academic / other
Locations2 sites (Indianapolis, Indiana and 1 other locations)
Trial IDNCT05733520 on ClinicalTrials.gov

What this trial studies

This study evaluates the effectiveness of the Brain CareNotes mobile health application in reducing caregiver burden and behavioral and psychological symptoms of dementia in patients with Alzheimer's disease. Over 39 months, 160 unpaid caregivers will be randomized to use either the Brain CareNotes app or an education-only control app for 12 months. The primary outcomes will measure caregiver-reported symptoms and distress using the Neuropsychiatric Inventory at baseline, six, and twelve months. Secondary outcomes will assess caregiver depressive symptoms and acute care utilization.

Who should consider this trial

Good fit: Ideal candidates are unpaid primary caregivers of community-dwelling individuals diagnosed with Alzheimer's disease or related dementias.

Not a fit: Patients who are permanent residents of extended care facilities or those with impairments preventing mobile device use may not benefit from this study.

Why it matters

Potential benefit: If successful, this intervention could significantly alleviate the burden on caregivers and improve the quality of life for both caregivers and patients.

How similar studies have performed: Other studies have shown promise in using mobile health applications to support caregivers, suggesting potential for success in this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Caregiver Inclusion Criteria:

* Self-identified primary unpaid caregiver of a person diagnosed with ADRD (at any stage) who are:
* Receiving primary care and
* Community-dwelling;
* English literate;
* Age ≥ 18 years

Caregiver Exclusion Criteria:

* Care recipient is a permanent resident of an extended care facility (nursing home);
* Involvement in another clinical trial that would prevent or interfere with study objectives;
* Sensory or other impairment prohibiting the use of a mobile touchscreen device or other study activity (after correction)

Where this trial is running

Indianapolis, Indiana and 1 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Caregiver BurdenAlzheimer DiseaseAlzheimer's disease and related dementiasCaregiverBehavioral and psychological symptoms of dementia
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.