MNK therapy for treating acute ankle sprains

Micro-needle-knife Therapy in Releasing the Superficial Fascia for Patients With Acute Ankle Sprain: an Assessor-blinded, Randomised Controlled Trial

NA · Affiliated Dongyang Hospital of Wenzhou Medical University · NCT06266520

This study tests if a new treatment called MNK therapy can help people with acute ankle sprains feel better compared to traditional acupuncture.

Quick facts

PhaseNA
Study typeInterventional
Enrollment80 (estimated)
Ages16 Years to 55 Years
SexAll
SponsorAffiliated Dongyang Hospital of Wenzhou Medical University (other)
Locations1 site (Dongyang, Zhejiang)
Trial IDNCT06266520 on ClinicalTrials.gov

What this trial studies

This clinical trial aims to evaluate the efficacy and safety of MNK therapy in releasing the superficial fascia for patients with acute ankle sprains. Participants will be randomly assigned to either receive MNK therapy or conventional acupuncture treatment. The study employs a blinded evaluator methodology to ensure unbiased assessment of outcomes. The goal is to provide valuable insights for clinical practitioners and patients regarding treatment options for acute ankle sprains.

Who should consider this trial

Good fit: Ideal candidates for this study are individuals aged 16 to 55 with a recent history of acute ankle sprain symptoms.

Not a fit: Patients with severe underlying conditions, those requiring surgery, or individuals with significant fear of needles may not benefit from this study.

Why it matters

Potential benefit: If successful, this therapy could offer a new, effective treatment option for patients suffering from acute ankle sprains.

How similar studies have performed: While this approach is relatively novel, similar studies have shown promising results in the treatment of soft tissue injuries.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* 16 to 55 years old
* Clear history of trauma within 1 to 7 days
* Presence of localized swelling, pain, bruising, and limping symptoms in the ankle joint
* Pain in the ankle joint upon resistance
* No accompanying fractures
* Diagnosis of acute ankle injury according to the "Diagnostic and Therapeutic Criteria of Traditional Chinese Medicine"
* No prior treatment before participating in this therapy
* Willingness to participate in this study and signing of the informed consent form

Exclusion Criteria:

* Individuals with clear indications for surgery
* Those suffering from gout, rheumatoid arthritis, joint tuberculosis, joint tumors, etc.
* Pregnant or breastfeeding women
* Individuals with serious primary diseases of the cardiovascular, liver, kidney, brain, and hematopoietic systems
* Those with local skin lesions or skin diseases
* Individuals with coagulation dysfunction
* Those with severe fear of needles
* Individuals unwilling to comply with the treatment regimen

Where this trial is running

Dongyang, Zhejiang

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Acute Ankle Sprain, acute ankle sprain, micro-needle-knife, superficial fascia, randomized controlled trial

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.