Minimally invasive treatments for thyroid cancer

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study focuses on the use of minimally invasive treatments, specifically image-guided thermal ablations, as an alternative to surgery for patients diagnosed with Papillary Thyroid Microcarcinoma (PTMC). It aims to establish a prospective registry to validate the safety and efficacy of these treatments while collecting long-term results from a large cohort of patients. The approach is designed to minimize complications and improve quality of life by precisely targeting the tumor while sparing surrounding thyroid tissue.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients \> 18years
* Patients with diagnosis of papillary thyroid microcarcinoma, citologically proven, suitable for MITT.
* Written informed consent must be signed and dated by the patient and the investigator prior to inclusion.
* Patients must be accessible for follow-up

Exclusion Criteria:

* Tumors \> 1 cm, other citological type, refusal of MITT, unsuitable for MITT, unmanageable coagulative disorders
* Patients with psychiatric, addictive, or any disorder, which compromises ability to give informed consent for participation in this study

Where it's running

• European Institute of Oncology
  Milan, Italy Recruiting

Study contacts

• Principal investigator: Giovanni Mauri — European Institute of Oncology
• Study coordinator: Giovanni Mauri
• Email: giovanni.mauri@ieo.it
• Phone: +390294372691

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Microwave ablation for papillary thyroid microcarcinoma monitored with contrast-enhanced ultrasound and genetic testing

  This project will try microwave ablation guided by contrast-enhanced ultrasound and an 88-gene panel in adults with low-risk papillary thyroid microcarcinoma to see if it controls the tumor while preserving thyroid function.

  Recruiting Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University · Guangzhou, Guangdong · NCT07054229

• Radiofrequency Ablation for Papillary Thyroid Microcarcinoma

  This study tests if a less invasive treatment called Radiofrequency Ablation can safely help people with small thyroid cancers who can’t or don’t want to have surgery.

  Recruiting Columbia University · New York, New York · NCT05189821

• Monitoring small thyroid cancers without immediate surgery

  This study tests whether watching small thyroid cancers closely instead of doing surgery right away is a safe option for patients and looks at how this choice affects their quality of life and anxiety.

  Recruiting Cedars-Sinai Medical Center · Los Angeles, California · NCT02609685

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.