Minimally invasive treatment for ureteropelvic junction obstruction in adults
Functional Outcome After Laparoscopic and Robot Assisted Management of Uretero-pelvic Junction Obstruction Disease Caused by Crossing Vessels for Adult Patients
This study is testing a new, less invasive surgery called vascular hitch to see if it works better than the traditional method for treating adults with ureteropelvic junction obstruction caused by crossing blood vessels.
Quick facts
| Phase | Phase 3 |
|---|---|
| Study type | Interventional |
| Enrollment | 17 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Cairo University Academic / other |
| Locations | 1 site (Cairo) |
| Trial ID | NCT05895422 on ClinicalTrials.gov |
What this trial studies
This clinical trial investigates the effectiveness of a minimally invasive technique called vascular hitch for treating adult patients with ureteropelvic junction obstruction (UPJO) caused by crossing vessels. Participants will be managed either through the traditional dismembered pyeloplasty or the newer vascular hitch approach. The study aims to compare the outcomes of these two methods, focusing on operative time and hospital stay. By utilizing robotic-assisted or laparoscopic techniques, the trial seeks to demonstrate potential advantages over the classic open surgical method.
Who should consider this trial
Good fit: Ideal candidates for this study are adults over 18 years old with symptomatic UPJO confirmed by CT angiography due to crossing vessels.
Not a fit: Patients with recurrent UPJO after previous open repair, secondary UPJO after renal surgery, or UPJO in non-functioning kidneys may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to less invasive surgical options for patients with UPJO, resulting in shorter recovery times and improved outcomes.
How similar studies have performed: Previous studies have shown promising results with minimally invasive techniques for UPJO, suggesting that this approach may be effective, though the vascular hitch technique is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * all patients with UPJO above 18 years * UPJO caused by crossing vessels confirmed by CT angiography * Symptomatic UPJO Exclusion Criteria: * recurrent UPJO after a previous trial of open repair , * secondary UPJO after open renal surgery. * UPJO in non functioning kidney
Where this trial is running
Cairo
- Faculty of Medicine — Cairo, Egypt (Recruiting)
Study contacts
- Study coordinator: Ahmed M Rammah, MD
- Email: ahmedrammah2013@gmail.com
- Phone: 2001005622939
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.