Minimally invasive treatment for chronic subdural hematoma using cyanoacrylate embolization

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial evaluates the efficacy of cyanoacrylate embolization as an adjuvant therapy for patients with chronic subdural hematoma (CSH) requiring surgical intervention. Participants will be divided into two groups: one receiving standard surgical management with additional embolization of the middle meningeal artery, and the other receiving only standard surgical management. The study aims to assess the recurrence rates of CSH and overall patient outcomes using specific scoring systems at two and six months post-treatment. The trial is designed to provide insights into the effectiveness of this minimally invasive approach compared to conventional methods.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patient with a more than 10 mm CSH confirmed by NCCT
* CSH localized to convexity
* Patient aged 18 years or more at the time of the enrollment
* Patient beneficiary from health insurance

Exclusion Criteria:

* Any contraindication as required per angiogram procedure (severe renal failure ≥ 4, allergy…)
* Pre-existing severe disability resulting in baseline mRS score \> 3
* Life expectancy of less than 6 months due to another cause than CSH
* Patient under legal protection or deprived of liberty by a judicial or administrative decision
* Pregnant or breastfeeding women
* Vulnerable persons unable to give consent

Where it's running

• CHU Brest
  Brest, France, France Recruiting
• Hôpital Henri Mondor
  Créteil, France, France Recruiting
• CHU Nantes
  Nantes, France, France Recruiting
• CHU Nice
  Nice, France, France Recruiting
• Hôpital Pitié Salpêtrière
  Paris, France, France Recruiting
• Hôpital Fondation Rothschild
  Paris, France, France Recruiting

Study contacts

• Study coordinator: jean-Christophe GENTRIC, PhD
• Email: jean-christophe.gentric@chu-brest.fr
• Phone: 0298347520

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Middle Meningeal Artery Embolisation to Prevent Recurrence of Chronic Subdural Hematoma

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• Coil embolization for unilateral vs bilateral chronic subdural hematomas

  This trial tests whether unilateral or bilateral coil-based embolization of the middle meningeal artery helps people with chronic subdural hematoma.

  Recruiting Lahey Clinic · Burlington, Massachusetts · NCT07715656

• Non-Thermal Plasma Used During Surgery to Help Prevent Recurrent Chronic Subdural Hematoma

  A randomized trial tests whether applying non-thermal plasma during standard surgery to drain a chronic subdural hematoma can reduce recurrence within 6 months.

  Recruiting National Institute of Nuclear Research - Mexico · Ocoyoacac, State of Mexico · NCT07656818

• Enhanced recovery pathway for burr-hole drainage in chronic subdural hematoma patients

  This project tests whether an enhanced recovery protocol for adults having burr-hole drainage for chronic subdural hematoma can reduce recurrence and complications compared with past patients.

  Recruiting Universitaire Ziekenhuizen KU Leuven · Leuven · NCT07421453

• Matched microcatheter and guidewire use for middle meningeal artery embolization in chronic subdural hematoma

  This will test whether using a matched Aristotle 14 guidewire and Plato 17 microcatheter during middle meningeal artery embolization works better than surgeons' usual device choices for adults with chronic subdural hematoma.

  Recruiting Ohio State University · Columbus, Ohio · NCT07324551

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.