Minimally invasive thoracic surgery without stopping aspirin

Routine Minimally Invasive Thoracic Surgery Without Aspirin Withdraw Before Surgery

Not applicable Interventional The Second Hospital of Shandong University · NCT05511441

This study tests if it's safe for patients with early-stage lung cancer or benign lung issues to have minimally invasive surgery while still taking their low-dose aspirin.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment60 (estimated)
Ages18 Years to 85 Years
SexAll
SponsorThe Second Hospital of Shandong University Academic / other
Locations1 site (Jinan, Tianqiao)
Trial IDNCT05511441 on ClinicalTrials.gov

What this trial studies

This study evaluates the safety of performing routine minimally invasive thoracic surgery while patients continue their long-term use of low-dose aspirin. It focuses on patients with stage I-IIIa non-small-cell lung cancer or benign lung lesions who require surgical intervention. The study aims to determine if continuous aspirin use during the perioperative period is safe, thereby addressing a common concern among surgeons regarding aspirin management in surgical patients.

Who should consider this trial

Good fit: Ideal candidates include patients with stage I-IIIa non-small-cell lung cancer or benign lung lesions who are undergoing minimally invasive thoracic surgery and can tolerate the procedure.

Not a fit: Patients with cardio-pulmonary function that cannot tolerate surgery or those at high risk of bleeding post-operatively may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could enhance surgical safety and outcomes for patients who rely on aspirin for cardiovascular protection.

How similar studies have performed: While the specific approach of this study is novel, similar studies have explored the management of aspirin in surgical settings, indicating potential for success.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. patients with stage I-IIIa Non-small-cell Lung Cancer underwent radical resection or other benign lung lesions need Minimally Invasive Thoracic Surgery;
2. VATS and robotic surgery are both permitted;
3. cardio-pulmonary function can tolerate surgery.

Exclusion Criteria:

1. cardio-pulmonary function couldn't tolerate surgery;
2. high bleeding risk after the pre- operative evaluation.

Where this trial is running

Jinan, Tianqiao

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Aspirin SensitivitySurgeryAspirinMinimally Invasive Thoracic SurgerySafety
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.