Minimally invasive surgery to remove deep (basal ganglia) brain hemorrhages

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a prospective, multicenter observational cohort enrolling consecutive adults with spontaneous basal ganglia intracerebral hemorrhage at two hospitals in Ho Chi Minh City. Patients with hematoma volume 30–80 mL and GCS 5–14 who present within 72 hours are followed, while treatment decisions (minimally invasive surgery versus medical management) are made by the treating teams in routine practice. Clinical, laboratory, and imaging data are recorded prospectively using standardized case report forms, and details of any MIS procedures are documented. Outcomes including survival and functional status are measured through 180 days.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age 18 to 80 years
* Spontaneous basal ganglia intracerebral hemorrhage confirmed by non-contrast CT scan
* Hematoma volume 30-80 mL (ABC/2 method)
* Time from onset/last known well ≤ 72 hours
* Glasgow Coma Scale (GCS) score 5-14 at admission
* Pre-stroke modified Rankin Scale (mRS) score 0-1

Exclusion Criteria:

* Secondary intracerebral hemorrhage due to trauma, tumor, vascular malformation, aneurysm, or hemorrhagic transformation of ischemic stroke
* Infratentorial hemorrhage (brainstem or cerebellum)
* Primary thalamic hemorrhage
* Extensive intraventricular hemorrhage (\>50% of one lateral ventricle)
* NIHSS \< 5 at admission
* Bilateral fixed dilated pupils without light reflex
* Decerebrate posture
* Platelet count \< 75,000/µL
* INR \> 1.4 after correction
* Ongoing anticoagulation that cannot be rapidly reversed
* Indication for long-term anticoagulation within 5 days of onset
* End-stage renal disease
* End-stage liver disease
* Presence of mechanical heart valve
* Any comorbidity with life expectancy \< 6 months
* Patient or legal representative unwilling or unable to provide written informed consent

Where it's running

• People's Hospital 115
  Ho Chi Minh City, Ho Chi Minh, Vietnam Recruiting

Study contacts

• Study coordinator: Huy Q Huynh, MD
• Email: dr.huynhquochuy@gmail.com
• Phone: +84 943054927

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.