Mindfulness program versus standard psychological follow-up during pregnancy

A Randomized Controlled Trial Comparing a Mindfulness-based Program With Standard Therapeutic Follow-up During Pregnancy: Effects on Maternal Well-being, Infant Outcomes, and Mother-Infant Attachment

Not applicable Interventional Universite Cote d'Azur · NCT07364032

This project will see if a 6-week mindfulness meditation program helps pregnant women (12–28 weeks) reduce stress, anxiety, sleep problems, and improve mood and bonding compared with standard therapeutic follow-up.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment70 (estimated)
Ages18 Years to 45 Years
SexFemale
SponsorUniversite Cote d'Azur Academic / other
Locations1 site (Mouans-Sartoux)
Trial IDNCT07364032 on ClinicalTrials.gov

What this trial studies

Pregnant women between 12 and 28 weeks gestation are randomized to a 6-week mindfulness meditation program or to standard psychological follow-up. The mindfulness arm includes one instructor-led meditation session per week plus five guided audio meditations to do at home each week. Outcomes measured include maternal negative and positive affect, maternal-fetal and maternal-infant attachment at multiple postpartum timepoints, mother-infant interaction quality, and infant sleep and crying measures up to 12 months. The program is delivered at a single site in Mouans-Sartoux, France, with follow-up assessments through the first year postpartum.

Who should consider this trial

Good fit: Pregnant women 12–28 weeks gestation who can read and speak French, are willing to be randomized, and are not already participating in other prenatal support programs are ideal candidates.

Not a fit: Women who have experienced pregnancy loss, are already enrolled in prenatal mindfulness or similar programs, or have severe unstable psychiatric disorders are unlikely to benefit or may be excluded.

Why it matters

Potential benefit: If effective, the program could lower maternal stress and mood symptoms during pregnancy and strengthen mother-infant bonding and early infant outcomes.

How similar studies have performed: Previous prenatal mindfulness studies have shown reductions in maternal stress and anxiety, but evidence for effects on infant attachment and longer-term infant outcomes is limited.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Pregnant women between 3 and 7.5 months of gestation (12-28 weeks).
* Ability to speak and read French sufficient to understand study documents and complete questionnaires.
* Willingness to participate in the study and to be randomized to one of the study groups.

Exclusion Criteria:

* Loss of the baby
* Participation in other prenatal support programs, including prenatal yoga, haptonomy, sophrology, or mindfulness courses.
* Severe or unstable psychiatric disorder. Inability to understand French or complete study questionnaires.

Where this trial is running

Mouans-Sartoux

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Mindfulness ProtocolsPregnancy
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.