Mindfulness-based programs for suicidal thoughts and self-harm in Korean youth

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This project develops two age-tailored, mindfulness-informed intervention programs—one for middle/high school students and one for young adults—and compares them to general mental health education using a randomized or quasi-experimental design. Clinical outcomes include suicidal ideation, self-injurious behavior, depressive symptoms, hopelessness, sleep, and emotion-regulation measures collected before and after the interventions. Biological measures include resting-state fMRI metrics (ALFF, ReHo, functional connectivity) and monitoring of social rhythm patterns to explore neurobiological and behavioral correlates of clinical change. The study also creates structured therapist and participant manuals and the first Korean clinical practice guidelines for adolescent and young adult suicide/self-harm care.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. General Criteria

   * Aged between 15 and 30 years
   * Obtained informed consent from a parent or legal guardian for participants under 19 years of age
2. For the Self-Harm Group

   * At least one incident of non-suicidal self-injury (NSSI) within the last 6 months
   * Self-Harm Screening Inventory (SHSI) score of at least 1 (at least one "Yes" response)
3. For the Suicide Attempt Group

   * Suicide attempt within the last 6 months
   * Depressive Symptom Inventory-Suicidality Subscale (DSI-SS) score of 3 or higher

Exclusion Criteria:

1. Psychiatric and Developmental Conditions

   * History of developmental disorders, including intellectual disability or autism spectrum disorder
   * Diagnosis of schizophrenia or bipolar disorder
   * Currently in an acute psychotic state
2. Medical and Physical Conditions

   * Presence of severe physical illness that interferes with daily life
   * Presence of metallic substances in the body (e.g., cardiac pacemakers, artificial heart valves) that are incompatible with fMRI
   * Diagnosis of claustrophobia
   * Current Treatment and Intervention
   * Currently receiving regular and active cognitive behavioral therapy (CBT)
   * Initiation of pharmacological treatment within the last 2 months
3. Communication and Consent

   * Inability to communicate fluently in Korean
   * Failure to obtain informed consent from a parent or legal guardian for participants under 19 years of age

Where it's running

• Ajou University Medical Center
  Suwon, Gyeonggi-do, South Korea Recruiting

Study contacts

• Study coordinator: Yunmi Shin, MD
• Email: ymshin@ajou.ac.kr
• Phone: +82-31-219-5180

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Multi-layered digital monitoring and pharmacogenomics to prevent suicide in adults with depression

  This study tests whether a digital monitoring system, a digital safety plan, and pharmacogenetic-guided care can reduce suicide re-attempts in adults with depression.

  Recruiting Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz · Madrid, Madrid · NCT07885722

• Youth suicide risk factors and personalized reduction strategies in young adults

  This study tests whether combining clinical data, genetic information, neuroimaging, and microbiome data can help identify risk factors and see if a dTMS-based intervention reduces suicide risk in young adults with mood disorders.

  Recruiting Fondazione Policlinico Universitario Agostino Gemelli IRCCS · Roma, RM · NCT07188506

• SAFETY family-based program for youths after a suicide attempt

  This project will test whether the SAFETY family-based therapy helps 10-17-year-olds who recently attempted suicide avoid repeat attempts.

  Recruiting at 4 sites Karolinska Institutet · Helsingborg and 4 other locations · NCT06931639

• Improving coping to reduce suicide risk after ED discharge

  This study tests whether an electronic safety plan and supportive text messages can help adults who have recently had suicidal thoughts or behaviors after leaving the emergency department.

  Recruiting University of Michigan · Ann Arbor, Michigan · NCT06614946

• Intensive Crisis Intervention for teens with suicidal thoughts or behaviors

  This project will try a brief, family-focused Intensive Crisis Intervention to see if it helps 12–17-year-olds with suicidal thoughts or recent attempts reduce suicidal behavior and avoid inpatient psychiatric care.

  Recruiting Nationwide Children's Hospital · Columbus, Ohio · NCT06476886

• Improving treatment for suicidal individuals with PTSD

  This study is testing if combining prolonged exposure therapy with a crisis response plan can help people with PTSD reduce their suicidal thoughts and behaviors better than standard treatment.

  Recruiting Ohio State University · Columbus, Ohio · NCT06285708

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.