Clinical trial Recruiting at 1 site Interventional Ages 16 and up

Microneedling with different treatments for hair loss

Official title: Comparative Study of Combined Microneedling With Either 1% Lactic Acid Solution or Vitamin D3 or Triamcinolone Acetonide in The Treatment of Alopecia Areata

Run by Zagazig University · NCT06327581 · Data updated 2026-11-12

This study is testing whether microneedling combined with different treatments can help people with alopecia areata grow their hair back.

More Alopecia Areata trials

Quick facts

Study typeInterventional
Ages16 Years and up
SexAll
Enrollment88 (estimated)
SponsorZagazig University
Government
Drugs / interventionsimmunotherapy, methotrexate
Locations1 site (Zagazig)
StatusRecruiting
StartedDecember 15, 2023
Main results expectedDecember 30, 2026
Study endsDecember 30, 2026
Registry record updatedJanuary 26, 2026
Trial IDNCT06327581 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are individuals aged 16 and older with localized patchy alopecia areata.

Probably not a fit

Patients with alopecia totalis, universalis, or those who have received recent treatments for alopecia may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial investigates the effectiveness of microneedling combined with various treatments—1% lactic acid, vitamin D3, and triamcinolone acetonide—in patients with alopecia areata. Participants will undergo microneedling sessions every two weeks for up to six sessions, with the aim of stimulating hair regrowth. The study will compare the outcomes of each treatment group to determine which combination is most effective in promoting hair restoration. Photographic documentation will be used to assess changes in hair growth throughout the treatment period.

Why it matters

Potential benefit: If successful, this approach could provide a new effective treatment option for patients suffering from alopecia areata.

How similar studies have gone: While there have been studies on microneedling for hair loss, the specific combinations being tested in this trial are novel and not widely explored.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* · Age ≥ 16 years old with localized patchy AA (up to 6 cm in diameter).

  * Patients of both sexes
  * Willing to participate in the study and to sign an informed consent.

Exclusion Criteria:

* · Patients who received systemic or topical treatment for AA in the last 3 months prior to the start of the study

  * Patients with Alopecia totalis, universalis, ophiasis, or sisaipho
  * Pregnant or lactating females
  * Patients who had bleeding or coagulation disorders
  * Immunocompromised patients
  * Patients with known history of hypersensitivity to vit D
  * Patients taking vitamin D supplements in the last 6 months.

Where it's running

  • Rana Ehab
    Zagazig, Egypt
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

  • Which works better for patchy hair loss: steroid injections or microneedling with steroid cream?

    This trial tests whether injecting triamcinolone into the skin or using microneedling with topical triamcinolone helps people with alopecia areata regrow hair more effectively.

    Recruiting Phase 4 Dow University of Health Sciences · Karachi, Sindh · NCT07926711

  • Red Ultraviolet Hair Imaging and Hair Growth in Alopecia Areata

    This observational study checks if red fluorescence seen with UV hair imaging relates to disease features and how well hair regrows after standard intralesional corticosteroid treatment in adults with limited plaque-type alopecia areata.

    Recruiting Istanbul Training and Research Hospital · Istanbul · NCT07803874

  • VC005 tablets in teens with severe alopecia areata

    This Phase 1 study tests VC005 tablets in adolescents with severe alopecia areata to see how the drug behaves in the body, whether it is safe, and if there are signs of benefit.

    Recruiting Phase 1 Jiangsu vcare pharmaceutical technology co., LTD · Beijing, Beijing Municipality · NCT07762443

  • VC005 tablets in severe alopecia areata

    This study tests whether VC005 tablets work better than a placebo for adults with severe alopecia areata.

    Recruiting Phase 2 Jiangsu vcare pharmaceutical technology co., LTD · Beijing, Beijing Municipality · NCT07749716

  • Ritlecitinib for patchy hair loss in teens and adults with alopecia areata

    This study tests whether ritlecitinib can help people 12 and older with patchy alopecia areata who have had symptoms for 6 months to 10 years.

    Recruiting at 30 sites Phase 3 Pfizer · Encinitas, California and 37 other locations · NCT07733765

  • Alopecia Areata: looking at ferroptosis markers in blood

    This study tests whether levels of GPX4 and MDA in blood differ between people with alopecia areata and healthy controls.

    Recruiting Istanbul Training and Research Hospital · Istanbul, Cerrahpasa Mahallesi · NCT07733063

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.