Clinical trial Recruiting at 1 site Interventional Men only

Microcurrent therapy after exercise in military personnel

Official title: Microcurrent Therapy and the Post-Exercise Physiological Response: Effects on Creatine Kinase and Associations With Lactate.

Run by University of Castilla-La Mancha · NCT07877337 · Data updated 2026-11-12

This trial tests whether active microcurrent therapy after exercise changes blood levels of creatine kinase in military personnel compared with a sham treatment.

Quick facts

Study typeInterventional
SexMen only
Enrollment20 (estimated)
SponsorUniversity of Castilla-La Mancha
Academic / other
Locations1 site (Toledo)
StatusRecruiting
StartedOctober 15, 2026
Main results expectedNovember 1, 2026
Study endsNovember 10, 2026
Registry record updatedOctober 28, 2026
Trial IDNCT07877337 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are healthy active-duty military personnel aged 18–45 without implanted electronic devices or skin issues in the thigh region, able to commit to the daily device use for seven hours per leg.

Probably not a fit

Participants with certain medical conditions or those not responding to microcurrent therapy may not experience changes in recovery markers.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

In this randomized, parallel-group study, 20 healthy active-duty military volunteers will complete a standardized exercise session and then receive either active microcurrent therapy or a sham device for seven hours per day on each leg during the 48-hour recovery window. Creatine kinase will be measured before exercise and at 24 and 48 hours post-exercise to compare the recovery patterns between groups, with lactate and perceived exertion assessed immediately after exercise. The study also evaluates practical use and tolerability of the post-exercise microcurrent intervention. Blinding is maintained for participants and outcome assessors, with separate personnel handling assignment and assessment.

Why it matters

Potential benefit: If successful, microcurrent therapy could help modulate muscle stress markers after exercise and support recovery.

How similar studies have gone: Prior research has explored post-exercise therapies to influence muscle recovery markers, but this exact microcurrent approach with blinded sham control is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age between 18 and 45 years.
* Active-duty military personnel.
* Healthy volunteers with current medical clearance.
* Skin over the quadriceps free of lesions, burns, or irritation.
* Availability and willingness to comply with the proposed intervention protocol.
* Informed consent form read and signed.

Exclusion Criteria:

* Implanted electronic devices: pacemakers, defibrillators, neurostimulators, etc.
* Neuromuscular disease or peripheral neuropathy.
* Treatment for HIV or chronic viral infections.
* Uncontrolled seizure disorders (active epilepsy).
* Uncontrolled, clinically significant heart disease.
* Depression.
* Uncontrolled hypertension.
* Thrombosis.
* Diabetes with neuropathy or impaired wound healing.
* Active neoplasms or suspected cancer.
* Recent musculoskeletal injuries (within the past three months) or chronic muscle pain in a lower limb.
* Recent major surgery.
* A dermatological condition in the quadriceps region.
* Prescription of medications that may confound pain assessment during the seven days before or during the intervention, including nonsteroidal anti-inflammatory drugs (NSAIDs), muscle relaxants, and systemic corticosteroids.
* Long-term treatment for hypercholesterolemia.
* Prescription of antipsychotic or neuroleptic medications.
* Long-term treatment for hypertriglyceridemia.
* Alcohol or other substance abuse.
* Inability to follow the intervention instructions.

Where it's running

  • Campus de Toledo de la Universidad de Castilla-La Mancha (UCLM)
    Toledo, Spain
    Recruiting

Study contacts

  • Principal investigator: Juan Avendaño-Coy, PhD — University of Castilla-La Mancha
  • Study coordinator: Juan Avendaño-Coy, PhD
  • Email: Juan.Avendano@uclm.es
  • Phone: +34 926051649

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.