Methods to reduce blood loss during laparoscopic myomectomy
Different Methods to Minimize Blood Loss During Laparoscopic Myomectomy; A Randomized Controlled Clinical Trial
NA · Zagazig University · NCT06566352
This study is testing two new methods to see if they can help reduce blood loss during laparoscopic surgery for women with uterine fibroids.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 60 (estimated) |
| Ages | 18 Years to 39 Years |
| Sex | Female |
| Sponsor | Zagazig University (other gov) |
| Locations | 1 site (Zagazig) |
| Trial ID | NCT06566352 on ClinicalTrials.gov |
What this trial studies
This clinical trial investigates the effectiveness of two techniques—temporary bilateral uterine artery occlusion and intramyometrial injection of diluted epinephrine—in minimizing blood loss during laparoscopic myomectomy. The study aims to compare these methods against traditional laparoscopic myomectomy to determine if they can reduce intraoperative bleeding, operation time, and hospitalization duration. It is the first of its kind at the university, focusing on improving surgical outcomes for women with uterine fibroids.
Who should consider this trial
Good fit: Ideal candidates for this study are women aged 18 to 39 with symptomatic uterine fibroids and no previous hormonal treatment.
Not a fit: Patients with bleeding tendencies, current pregnancy, or those who have had more than one cesarean delivery may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to safer laparoscopic myomectomy procedures with reduced blood loss and shorter recovery times for patients.
How similar studies have performed: While this approach is novel at this institution, similar studies have shown promising results in minimizing blood loss during surgical procedures.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Women aged from 18 to 39 years. 2. Symptomatizing Women (heavy menstrual bleeding or subfertility). 3. FIGO stage (3-7) by ultrasound. 4. Only uterine corpus fibroid. 5. Up to three fibroids by ultrasound. 6. No previous hormonal treatment. Exclusion Criteria: 1. Patients with bleeding tendency. 2. Patients who refuse to participate in the study or uncooperative patients. 3. Current pregnancy. 4. Any retroperitoneal surgery at pararectal space. 5. More than one cesarean delivery.
Where this trial is running
Zagazig
- Zagazig University — Zagazig, Egypt (RECRUITING)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Different Methods to Minimize Blood Loss During Laparoscopic Myomectomy