Melanoma in adults aged 18 to 39.
Demographic, Clinical, Dermoscopic, Phenotypic and Genetic Characteristics of Adult Patients With Melanoma Diagnosis <40 Years Age. A Prospective, Monocentric Observational Study
This project will collect clinical, dermoscopic, pathology, and molecular data to see how common melanoma is and what risk factors and skin features it has in people aged 18–39.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 25 (estimated) |
| Ages | 18 Years to 39 Years |
| Sex | All |
| Sponsor | Ente Ospedaliero Ospedali Galliera Academic / other |
| Locations | 1 site (Genoa, Liguria) |
| Trial ID | NCT06994208 on ClinicalTrials.gov |
What this trial studies
This observational cohort will gather clinical records, dermoscopic images, and histopathology from patients aged 18–39 diagnosed with cutaneous melanoma at E.O. Ospedali Galliera in Genoa. Investigators will record demographics, known risk factors, lesion phenotype, and dermoscopic features and correlate these with histological findings. Available tumor samples will be tested for BRAF mutations to explore molecular patterns in young patients. The analysis will describe prevalence in this age group and relate clinical appearance to pathology and mutation status.
Who should consider this trial
Good fit: Adults aged 18 to 39 with a diagnosis of cutaneous melanoma (including non-primary lesions) who can provide written informed consent.
Not a fit: People outside the 18–39 age range, those with non-cutaneous melanoma, or those expecting experimental treatment should not expect direct therapeutic benefit from this observational project.
Why it matters
Potential benefit: If successful, the findings could help clinicians recognize melanoma earlier in young adults and guide prevention and follow-up strategies.
How similar studies have performed: Previous observational series have described risk factors, dermoscopic features, and BRAF mutation frequencies in younger melanoma patients, so this work builds on established findings.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. written informed consent 2. age \> 18 years and \< 40 years 3. diagnosis of cutaneous melanoma even non-primary Exclusion Criteria: \-
Where this trial is running
Genoa, Liguria
- E.O. Ospedali Galliera — Genoa, Liguria, Italy (Recruiting)
Study contacts
- Principal investigator: Sanja Javor — Ente Ospedaliero Ospedali Galliera
- Study coordinator: Sanja Javor, MD
- Email: sanja.javor@galliera.it
- Phone: +390105634271
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.