Measuring water turnover in Chinese adults using deuterium dilution
Official title: Study on Water Turnover of the Chinese Population Based on Deuterium Dilution Method
Run by Shenzhen Institutes of Advanced Technology ,Chinese Academy of Sciences · NCT07028021 · Data updated 2026-11-12
This project will test how quickly Chinese adults replace their body water using a safe deuterium dilution method to help personalize hydration advice.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 300 (estimated) |
| Sponsor | Shenzhen Institutes of Advanced Technology ,Chinese Academy of Sciences Academic / other |
| Locations | 1 site (Beijing, Beijing Municipality) |
| Status | Recruiting |
| Started | May 6, 2025 |
| Main results expected | June 30, 2026 |
| Study ends | October 30, 2026 |
| Registry record updated | June 19, 2025 |
| Trial ID | NCT07028021 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are healthy Chinese adults with stable body weight who can attend in-person visits in Beijing and are not pregnant, breastfeeding, or taking diuretics.
✕Probably not a fit
People with chronic diseases affecting fluid balance, pregnant or breastfeeding individuals, and those on medications that change urine output are unlikely to directly benefit from this observational protocol.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational project measures total body water turnover in Chinese adults using the deuterium dilution technique alongside standard body composition and height measures. Participants provide a baseline urine sample after an overnight fast, drink a calculated dose of deuterated water, and give follow-up urine samples three and four hours later to calculate total body water. Height is measured with a Seca 217 stadiometer and body composition with a TANITA MC-780, while physical activity is monitored by a GT3 accelerometer worn near the hip for seven days. Daily water intake is recorded over the monitoring period and participants with chronic diseases, pregnancy, breastfeeding, or diuretic use are excluded.
Why it matters
Potential benefit: If successful, this work could support more personalized hydration recommendations and reduce risks tied to under- or over-hydration.
How similar studies have gone: Deuterium dilution is a well-established gold-standard method for measuring total body water, though using it to derive personalized population-wide intake guidelines remains relatively limited.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Stable body weight over the past year 2. Ability to perform normal physical activities Exclusion Criteria: 1. History of chronic diseases such as diabetes, liver disease, kidney disease, or any other conditions that may affect fluid metabolism 2. Use of diuretics or other medications that influence urine output 3. Pregnancy or breastfeeding
Where it's running
-
Beijing
Beijing, Beijing Municipality, China Recruiting
Study contacts
- Study coordinator: Xueying Zhang
- Email: zhangxy@siat.ac.cn
- Phone: +8618201296155
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.