Measuring walking quality in people with Multiple Sclerosis using camera technology

Development of Camera Based Gait Deviation Index for Persons With Multiple Sclerosis

Shirley Ryan AbilityLab · NCT06516458

This study is testing a new tool that uses camera technology to measure how well people with Multiple Sclerosis walk, to help doctors improve their treatment plans.

Quick facts

Study typeObservational
Enrollment40 (estimated)
Ages18 Years to 75 Years
SexAll
SponsorShirley Ryan AbilityLab (other)
Locations1 site (Chicago, Illinois)
Trial IDNCT06516458 on ClinicalTrials.gov

What this trial studies

This study aims to develop a new measurement tool called the Gait Deviation Index (GDI) specifically for individuals with Multiple Sclerosis (MS). By utilizing camera-based tracking to analyze body position during walking, the study seeks to create an objective and easily interpretable measure of gait quality. The GDI has previously been validated for spinal cord injury patients, but this research will adapt it for MS patients, enabling clinicians to better track progress and tailor rehabilitation strategies. Ultimately, the goal is to enhance the effectiveness of therapy for those living with MS.

Who should consider this trial

Good fit: Ideal candidates for this study are adults aged 18 to 75 with a diagnosis of relapsing form of Multiple Sclerosis who can walk independently and have been relapse-free for at least one month.

Not a fit: Patients with orthopedic injuries or other conditions that affect their ability to walk will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide clinicians with a reliable tool to assess and improve walking quality in patients with Multiple Sclerosis.

How similar studies have performed: While the Gait Deviation Index has shown success in spinal cord injury populations, its application in Multiple Sclerosis is novel and untested.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion criteria:

* Diagnosis of relapsing form of MS (including relapsing-remitting MS and secondary progressive MS)
* Able to ambulate overground
* Relapse free for at least 1 month
* Age ≥18 and ≤ 75 years
* Participants using dalfampridine will be eligible if taking the same daily dose for at least 2 months prior to screening

Exclusion criteria:

\- Orthopedic injuries, fractures, surgeries or other conditions affecting locomotor function or weight bearing

Where this trial is running

Chicago, Illinois

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Multiple Sclerosis, Multiple Sclerosis, Secondary Progressive, Multiple Sclerosis Relapse, Multiple Sclerosis, Relapsing-Remitting

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.