Measuring thoracic fluid to predict weaning from mechanical ventilation in ARDS patients

Thorathic Fluid Content as an Early Predictor of Weaning From Mechanical Ventilation in Acute Respiratory Distress Syndrome

Observational Tanta University · NCT06233448

This study tests if measuring fluid in the chest can help doctors know when patients with ARDS are ready to stop using a ventilator after being on it for more than two days.

Quick facts

Study typeObservational
Enrollment50 (estimated)
Ages18 Years to 60 Years
SexAll
SponsorTanta University Academic / other
Locations1 site (Tanta)
Trial IDNCT06233448 on ClinicalTrials.gov

What this trial studies

This observational study aims to evaluate the use of thoracic fluid content measurement through indirect cardiometry as a predictor for successful weaning from mechanical ventilation in patients suffering from Acute Respiratory Distress Syndrome (ARDS). By monitoring fluid levels, the study seeks to identify patients who are ready for extubation after being on a ventilator for more than 48 hours. The methodology focuses on assessing the relationship between thoracic fluid content and the outcomes of weaning from mechanical ventilation. The findings could provide valuable insights into improving patient management in critical care settings.

Who should consider this trial

Good fit: Ideal candidates for this study are patients diagnosed with ARDS who have been on mechanical ventilation for more than 48 hours and are being considered for extubation.

Not a fit: Patients with heart, renal, or hepatic failure, as well as those who are obese, pregnant, or have conditions like pneumothorax, pneumonia, or hemorrhage, may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could enhance the ability to safely wean patients from mechanical ventilation, potentially reducing complications and improving recovery times.

How similar studies have performed: While the specific approach of using indirect cardiometry for this purpose may be novel, similar studies have explored fluid management and monitoring in ARDS patients with varying degrees of success.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* patients with ARDS on ventilator for more than 48 hr. proceed for extubation

Exclusion Criteria:

* heart, renal, hepatic failure Obesity , pregnancy Pneumothorax, pneumonia, hemorrhage

Where this trial is running

Tanta

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Acute Respiratory Distress Syndrome
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.