Measuring the optic nerve sheath diameter using ocular ultrasound
Microconvex Probe Versus Linear Probe for Measurement of the Optic Nerve Sheath Diameter
NA · Cleveland Clinic Akron General · NCT05548335
This study tests if using ultrasound can accurately measure the optic nerve sheath and eyeball size in healthy adults who come to the Emergency Department.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 30 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Cleveland Clinic Akron General (other) |
| Locations | 1 site (Akron, Ohio) |
| Trial ID | NCT05548335 on ClinicalTrials.gov |
What this trial studies
This study evaluates the accuracy of ocular ultrasound in measuring the diameter of the optic nerve sheath and the eyeball transverse diameter in healthy adults visiting the Emergency Department. It involves a prospective assessment where adult patients who have normal confirmatory imaging of the optic nerve will be asked to participate. All participants will undergo identical ultrasound procedures using microconvex and linear transducers to gather data. The study is conducted at Cleveland Clinic Akron General between July 2022 and April 2023.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 and older who present to the Emergency Department with normal CT imaging of the head and/or eyes.
Not a fit: Patients with acute ocular pathology, abnormal CT findings, or those with a history of increased intracranial pressure will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance the accuracy of diagnosing optic nerve conditions in emergency settings.
How similar studies have performed: While the use of ocular ultrasound is established, this specific assessment of optic nerve sheath diameter in an emergency setting is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion criteria: * 18 years of age and older, and; * Present to Cleveland Clinic Akron General's ED (Main) * Have CT head and/or ocular ordered as a part of clinical care that is read as normal or no acute disease (confirmatory imaging), and; * Agree to and provide written consent for participation. Exclusion criteria: * Acute ocular pathology * Abnormal brain and/or ocular CT * History of increased intracranial pressure or optic nerve disease * Not medically stable * Pregnant or incarcerated * Unable to consent.
Where this trial is running
Akron, Ohio
- Cleveland Clinic Akron General — Akron, Ohio, United States (RECRUITING)
Study contacts
- Principal investigator: Joshua Jacquet, MD — Cleveland Clinic Akron General
- Study coordinator: Joshua Jacquet, MD
- Email: jacquej3@ccf.org
- Phone: 330-344-6000
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Optic Nerve, ocular ultrasound, optic nerve sheath diameter, ETD