Measuring skin carotenoid levels with a new portable Prysm scanner.
Study on Carotenoid-Based Instrumental Index
This project will test a new portable Prysm skin scanner in Chinese adults to measure carotenoid levels and see if those levels relate to diet and lifestyle.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 600 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | ChinaNorm Industry-sponsored |
| Locations | 1 site (Shanghai, Shanghai Municipality) |
| Trial ID | NCT07198503 on ClinicalTrials.gov |
What this trial studies
This observational study uses a Prysm biophotonic scanner based on Raman spectroscopy to measure skin carotenoid levels via hand scans in adult Chinese volunteers. Participants provide demographic and lifestyle information and undergo measurements including BMI, body fat percentage, standardized skin imaging (ITA°, L*, a*, b*, glossiness, erythema, pigmentation) and questionnaires on diet, skin condition, physical and psychological health, and memory. No interventions are administered; collected data will be analyzed to determine relationships between skin carotenoid signals and self-reported dietary and lifestyle factors and to validate the portable device in a population sample. Eligibility requires Chinese adults able to complete Chinese-language questionnaires and willing to consent, while those with active facial lesions, pregnancy or breastfeeding, severe acute illness treatment, or significant cognitive impairment are excluded.
Who should consider this trial
Good fit: Chinese adults (18 years or older) of Asian ethnicity who can read and write Chinese, are willing to provide informed consent, and can comply with the assessment procedures are ideal candidates.
Not a fit: Individuals who are pregnant or breastfeeding, have open facial lesions or significant acne scarring, are undergoing treatment for severe acute illnesses, or have major cognitive or behavioral impairments are unlikely to benefit or qualify for participation.
Why it matters
Potential benefit: If successful, the Prysm device could offer a low-cost, noninvasive way for people and clinicians to monitor dietary carotenoid status and aspects of skin health.
How similar studies have performed: Other Raman-based commercial skin carotenoid scanners have previously shown correlations with dietary carotenoid intake, and this device adapts that approach into a lower-cost, portable form.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Chinese individuals of Asian ethnicity aged 18 years or older. 2. Basic proficiency in reading and writing Chinese, sufficient to independently complete questionnaires. 3. Voluntary participation with signed informed consent. 4. Willingness to comply with all assessment requirements. Exclusion Criteria: 1. Presence of open facial lesions, prominent scars, or visible acne marks. 2. Currently planning pregnancy, pregnant, or breastfeeding. 3. Ongoing treatment for acute or severe medical conditions. 4. Significant impairments affecting cognitive or behavioral abilities. 5. Other medical reasons identified by experts or professionals that may interfere with the assessment results.
Where this trial is running
Shanghai, Shanghai Municipality
- Shanghai China-norm Quality Technical Service Co., Ltd. — Shanghai, Shanghai Municipality, China (Recruiting)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.