Measuring sevoflurane levels in children during anesthesia

Sevoflurane Concentrations During Induction of Anesthesia With the Drager Apollo and GE Ohmeda Workstations in Children

State University of New York at Buffalo · NCT06510803

This study is testing how much sevoflurane, a common anesthesia gas, is in the bodies of healthy children aged 2-6 during the first 10 minutes of their surgery.

Quick facts

Study typeObservational
Enrollment28 (estimated)
Ages2 Years to 7 Years
SexAll
SponsorState University of New York at Buffalo (other)
Locations1 site (Buffalo, New York)
Trial IDNCT06510803 on ClinicalTrials.gov

What this trial studies

This observational study aims to record sevoflurane concentrations and vital signs in healthy children aged 2-6 years undergoing minor elective surgery under general anesthesia. The study will adhere to standard anesthetic management while specifically monitoring the anesthetic gas concentrations during the first 10 minutes of anesthesia induction. A total of 28 children will be enrolled, with data collected from two different anesthesia workstations at Oishei Children's Hospital in Buffalo, NY. Consent will be obtained from parents, with provisions for translation services as needed.

Who should consider this trial

Good fit: Ideal candidates are healthy children aged 2-6 years scheduled for elective surgery under general anesthesia.

Not a fit: Patients with moderate or severe cardiorespiratory disease, difficult airway, or other specified exclusions may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could enhance the understanding of sevoflurane use in pediatric anesthesia, potentially leading to improved safety and efficacy.

How similar studies have performed: While this approach is observational and may not have been extensively tested in this specific context, similar studies on anesthetic monitoring have shown promising results.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion

* scheduled for elective surgery under general anesthesia,
* ASA physical status 1 or 2

Exclusion Criteria:

* parents refuse consent
* presence of moderate or severe cardiorespiratory disease
* difficult airway
* malignant hyperthermia
* neuromuscular disorders
* obesity
* obstructive sleep apnea

Where this trial is running

Buffalo, New York

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Anesthetic, Sevoflurane, Age, sevoflurane, anesthesia, children

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.