Measuring Relaxin Levels During Different Endometrial Preparation for Frozen Embryo Transfer

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the levels of Relaxin hormone in women undergoing different endometrial preparation methods for frozen embryo transfer (FET). It compares the natural proliferative phase approach, which monitors follicle growth and induces secretory transformation with progesterone, to hormonal replacement therapy (HRT) methods. The goal is to determine whether a functional corpus luteum, which produces Relaxin, is present in the natural approach, as this could impact pregnancy outcomes. The study aims to clarify the implications of these preparation methods on early pregnancy complications and overall success rates.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* regular menstrual cycles

Exclusion Criteria:

* abnormal findings of the ovaries (e.g endometriosis)
* Intake of any hormones within 3 months of study start
* desire to become pregnant

Where it's running

• ART Fertiltiy Clinic
  Abu Dhabi, Abu Dhabi Emirate, United Arab Emirates Recruiting

Study contacts

• Principal investigator: Barbara Lawrenz, PhD — ART Fertility Clinic
• Study coordinator: Barbara Lawrenz, M.D. PhD
• Email: barbara.lawrenz@artfertilityclinics.com
• Phone: 800 337845489

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Evaluating the convenience of natural cycle frozen embryo transfer

  This study looks at whether a new method for frozen embryo transfer that uses the body's natural cycle is easier and more convenient for patients compared to the traditional method that relies on medication.

  Recruiting Instituto Valenciano de Infertilidade de Lisboa · Lisbon · NCT06307184

• Comparing two methods for preparing the uterus for frozen embryo transfer in women with adenomyosis

  This study tests two different ways to prepare the uterus for frozen embryo transfer in women with adenomyosis to see which one helps achieve more successful pregnancies.

  Recruiting Mỹ Đức Hospital · Ho Chi Minh City, Ho Chi Minh City · NCT06239376

• Endometrial Waves and Pregnancy in FET Cycles with Hormone Therapy

  This study tests whether patterns of uterine contractions during hormone-prepared frozen embryo transfer affect pregnancy outcomes.

  Recruiting Mỹ Đức Hospital · Ho Chi Minh City · NCT07675213

• Comparing two vaginal progesterone forms for frozen embryo transfer

  This compares whether soft vaginal progesterone capsules are easier to use, better tolerated, and give similar pregnancy results as vaginal progesterone pessaries for women having frozen embryo transfer.

  Recruiting Instituto Valenciano de Infertilidade de Lisboa · Lisbon · NCT07461909

• FET-LET-2x2: Testing natural vs medicated natural cycles for frozen embryo transfer

  This study tests four approaches to preparing the uterus for frozen embryo transfer to see which yields the best pregnancy rate in women undergoing IVF.

  Recruiting University of Novi Sad · Novi Sad · NCT07425990

• How frozen embryo transfer preparation affects uterine wave activity

  We will test whether preparing for frozen embryo transfer with hormones or using a natural cycle changes uterine contractions in women having FET.

  Recruiting Mỹ Đức Hospital · Ho Chi Minh City and 1 other locations · NCT07358468

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.