Measuring Relaxin Levels During Different Endometrial Preparation for Frozen Embryo Transfer
Relaxin Measurement in Different Endometrial Preparation Approaches for Frozen Embryo Transfer
ART Fertility Clinics LLC · NCT06526520
This study is testing how different methods of preparing the uterus for frozen embryo transfer affect the levels of a hormone called Relaxin in women to see if it impacts pregnancy success.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 5 (estimated) |
| Ages | 18 Years to 35 Years |
| Sex | Female |
| Sponsor | ART Fertility Clinics LLC (other) |
| Locations | 1 site (Abu Dhabi, Abu Dhabi Emirate) |
| Trial ID | NCT06526520 on ClinicalTrials.gov |
What this trial studies
This study investigates the levels of Relaxin hormone in women undergoing different endometrial preparation methods for frozen embryo transfer (FET). It compares the natural proliferative phase approach, which monitors follicle growth and induces secretory transformation with progesterone, to hormonal replacement therapy (HRT) methods. The goal is to determine whether a functional corpus luteum, which produces Relaxin, is present in the natural approach, as this could impact pregnancy outcomes. The study aims to clarify the implications of these preparation methods on early pregnancy complications and overall success rates.
Who should consider this trial
Good fit: Ideal candidates for this study are women with regular menstrual cycles who are preparing for a frozen embryo transfer.
Not a fit: Patients with abnormal ovarian findings, recent hormone intake, or those desiring pregnancy may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved protocols for frozen embryo transfers, potentially reducing early pregnancy complications.
How similar studies have performed: While some studies have explored hormonal effects on embryo transfer, this specific approach comparing Relaxin levels in different preparation methods is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * regular menstrual cycles Exclusion Criteria: * abnormal findings of the ovaries (e.g endometriosis) * Intake of any hormones within 3 months of study start * desire to become pregnant
Where this trial is running
Abu Dhabi, Abu Dhabi Emirate
- ART Fertiltiy Clinic — Abu Dhabi, Abu Dhabi Emirate, United Arab Emirates (RECRUITING)
Study contacts
- Principal investigator: Barbara Lawrenz, PhD — ART Fertility Clinic
- Study coordinator: Barbara Lawrenz, M.D. PhD
- Email: barbara.lawrenz@artfertilityclinics.com
- Phone: 800 337845489
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Frozen Embryo Transfer, frozen embryo transfer, hormonal replacement cycle, natural cycle, Relaxin