Measuring reflux symptoms in children with cystic fibrosis after stopping GERD treatment

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to assess reflux symptoms in children aged 6-17 with cystic fibrosis who are currently receiving treatment for gastroesophageal reflux disease (GERD). Participants will complete a survey to evaluate their symptoms after discontinuing GERD therapy. The study will monitor changes in symptoms to better understand the impact of stopping treatment on this patient population. The goal is to gather data that could inform future treatment approaches for managing GERD in children with cystic fibrosis.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Children 2-18 years of age with a confirmed CF diagnosis by either a positive sweat test or 2 disease causing CFTR mutations.
* Signed consent

Exclusion Criteria:

* Declining to participate in the study or sign consent
* History of severe GERD per gastroenterology diagnosis and documentation
* GSAS score \>80

Where it's running

• Duke University Hospital
  Durham, North Carolina, United States Recruiting

Study contacts

• Principal investigator: Shatha Yousef — Duke University Hospital
• Study coordinator: Yara Salameh, MF
• Email: yara.salameh@duke.edu
• Phone: 919-684-8111

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.