Clinical trial Recruiting at 1 site Observational Ages 40 to 80

Measuring quality of life changes in Parkinson's patients

Official title: Determination of the Minimal Detectable Change and Minimum Clinically Important Change Score of the Parkinson's Disease Questionnaire-8

Run by Karadeniz Technical University · NCT06487364 · Data updated 2026-11-12

This study is testing how much a 30-session physiotherapy program can improve the quality of life for people with Parkinson's disease by using a questionnaire to track changes.

Quick facts

Study typeObservational
Ages40 Years to 80 Years
SexAll
Enrollment39 (estimated)
SponsorKaradeniz Technical University
Academic / other
Locations1 site (Istanbul)
StatusRecruiting
StartedMay 13, 2024
Main results expectedJanuary 17, 2025
Study endsSeptember 17, 2025
Registry record updatedMarch 5, 2025
Trial IDNCT06487364 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates include Parkinson's patients in stages 1-3 of the Hoehn and Yahr Scale who are receiving regular neurological follow-up and medication.

Probably not a fit

Patients with secondary neurological diseases, recent surgeries affecting the upper extremities, or significant psychological issues may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to determine the minimal detectable change in the Parkinson's Disease Questionnaire-8 (PDQ-8), which assesses the quality of life in patients with Parkinson's disease. Participants undergoing a 30-session physiotherapy program will report their quality of life changes before and after treatment using the PDQ-8 and Global Rating of Patient-Perceived Changes (GRP-PC) forms. The study will help establish how much improvement in PDQ-8 scores is considered significant for patients.

Why it matters

Potential benefit: If successful, this study could provide a clearer understanding of meaningful quality of life improvements for Parkinson's patients undergoing rehabilitation.

How similar studies have gone: While similar studies have explored quality of life measures in Parkinson's disease, this specific approach to determining minimal detectable change is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Having regular neurology follow-up and using medicine;
* Hoehn and Yahr Scale Stage between 1-3 points;
* Mini-Mental State Assessment Score \>24 points;

Exclusion Criteria:

* Having a secondary neurological disease;
* Any surgery and/or trauma affecting the upper extremity
* Having complaints of pain before the treatment program;
* There was a change in medical treatment during the study;
* With symptoms of anxiety and depression;
* Those who use alcohol and drugs;
* Individuals with vision defects that cannot be corrected by the use of glasses and those with hearing loss

Where it's running

  • Private Güney Hospital
    Istanbul, Turkey (Türkiye)
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.