Measuring Pupillary Response in Children with Brain Injuries After Osmotherapy

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to evaluate the effectiveness of quantitative pupillometry in assessing pupillary reactivity in children with brain injuries, particularly those experiencing intracranial hypertension. By using advanced pupillometers, the study seeks to provide objective measurements of pupillary constriction and reactivity, which are critical indicators of neurological status. The research will focus on children admitted to pediatric intensive care units within 24 hours of suspected intracranial hypertension, and it will analyze changes in pupillary response following osmotherapy treatment. The goal is to improve the identification and management of intracranial hypertension in pediatric patients.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Hospitalized in a pediatric intensive care unit or neurosurgical intensive care unit
* Inclusion within 24 hours of ICU admission
* with clinically suspected HTIC (disorders of consciousness with transcranial Doppler abnormality, symptoms of involvement, poor cerebral perfusion pressure) for which osmotherapy is prescribed

Exclusion Criteria:

* Presence of eye damage (or antecedent)
* Refusal by parents and/or child Opposition by child or parental guardians.
* Persons not affiliated to the social security system.
* Protected persons (under guardianship, curatorship, pregnant or breast- feeding women, persons deprived of their liberty, persons not subject to a psychiatric measure

Where it's running

• Chu Grenoble Alpes
  Grenoble, Isere, France Recruiting
• Grenoble Alpes University Hospital
  La Tronche, France Not yet recruiting

Study contacts

• Study coordinator: Sarah SS SINTZEL STRIPPPOLI, Doctor
• Email: ssintzelstrippoli@chu-grenoble.fr
• Phone: 0476766729

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.