Measuring Pain in Patients with Cognitive Deterioration Using EEG

Exploring Objective Pain Assessment in Individuals With Cognitive Deterioration: Electroencephalographic Markers and Machine Learning Analysis

Observational Azienda USL Toscana Nord Ovest · NCT06256666

This study is testing a new way to measure pain in older adults with cognitive issues using brain wave technology to help doctors better manage their pain after surgery.

Quick facts

Study typeObservational
Enrollment30 (estimated)
Ages70 Years to 100 Years
SexAll
SponsorAzienda USL Toscana Nord Ovest Academic / other
Locations1 site (Volterra, Pisa)
Trial IDNCT06256666 on ClinicalTrials.gov

What this trial studies

This research focuses on improving pain assessment in individuals with cognitive deterioration (CD), a common issue in aging and neurological conditions. The study utilizes electroencephalography (EEG) and machine learning to objectively measure pain, addressing the challenges faced by patients who cannot self-report their pain accurately. By employing a BIS device, the research aims to identify specific EEG markers associated with pain and compare these findings with an objective pain assessment scale. The study is particularly relevant for patients in surgical departments, where accurate pain management is crucial.

Who should consider this trial

Good fit: Ideal candidates for this study are individuals exhibiting at least moderate cognitive impairment.

Not a fit: Patients who are unable to provide consent will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to more accurate pain assessment and management for patients with cognitive deterioration.

How similar studies have performed: Other studies have explored similar approaches, but this specific application of EEG for pain assessment in CD patients is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Subjects exhibiting at least moderate cognitive impairment as assessed by the Pfeiffer scale.

Exclusion Criteria:

* lack of consent

Where this trial is running

Volterra, Pisa

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Cognitive DeteriorationCognitive deteriorationPain assessmentQuantitative electroencephalography
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.