Measuring muscle properties in COPD patients
Mechanical Properties of Peripheral and Accessory Respiratory Muscles in Chronic Obstructive Pulmonary Disease Patients
This study is testing how the muscles used for breathing in people with COPD work compared to healthy individuals to better understand their differences.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 66 (estimated) |
| Ages | 18 Years to 75 Years |
| Sex | All |
| Sponsor | Istanbul Medipol University Hospital Academic / other |
| Locations | 1 site (Istanbul, Zeytinburnu) |
| Trial ID | NCT06201403 on ClinicalTrials.gov |
What this trial studies
This observational study aims to assess the biomechanical properties of accessory and peripheral respiratory muscles in patients with Chronic Obstructive Pulmonary Disease (COPD) compared to healthy individuals. Using the MyotonPro device, the study will measure and analyze muscle characteristics to understand differences in muscle function related to COPD. The research focuses on patients diagnosed with group C and D COPD according to GOLD staging, ensuring they have stable medication regimens and no significant comorbidities. Healthy participants will also be included for comparative analysis.
Who should consider this trial
Good fit: Ideal candidates include adults diagnosed with group C and D COPD who have stable medication regimens and no significant comorbid conditions.
Not a fit: Patients with other respiratory diseases, recent COPD exacerbations, or those with conditions affecting measurement quality may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance understanding of respiratory muscle function in COPD, potentially leading to improved management strategies for patients.
How similar studies have performed: While the specific approach of measuring muscle properties in COPD patients may be novel, similar studies have explored respiratory muscle function and have shown varying degrees of success.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Being diagnosed with group C and D COPD according to GOLD staging * Having been using the same medications for the last 4 weeks * No additional comorbid diseases of the orthopedic, neurological or cardiac system Exclusion Criteria: * Presence of another respiratory system disease other than COPD * Patients who have had an acute COPD exacerbation in the last 4 weeks * Patients experiencing COPD exacerbations during the study protocol * Presence of fatty tissue at the measurement points, which may impair the measurement quality. * Have already participated in another clinical trial within the last 30 days that may affect the results of the study. Inclusion Criteria for Healthy Cases * Being over 18 years of age * Not having any diagnosed chronic disease * Not being a smoker
Where this trial is running
Istanbul, Zeytinburnu
- Yedikule Chest Disease Hospital — Istanbul, Zeytinburnu, Turkey (Türkiye) (Recruiting)
Study contacts
- Study coordinator: Esra Pehli̇van
- Email: fztesrakambur@yahoo.com
- Phone: 09050585279
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.