Measuring lung filling and emptying speed using ultrasound
Pulsed Eco Doppler for the Study of Polmonal Discharge Velocity: Pilot/Explorative Study
This study is testing how quickly the lungs fill and empty using ultrasound to help both healthy people and those with lung diseases understand lung movement better.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 100 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | IRCCS Azienda Ospedaliero-Universitaria di Bologna Academic / other |
| Locations | 2 sites (Bologna and 1 other locations) |
| Trial ID | NCT06815198 on ClinicalTrials.gov |
What this trial studies
This observational study aims to investigate the speed of lung filling and emptying by analyzing the characteristics of pulsed Doppler waves during respiration. It utilizes chest ultrasound to visualize lung motion during inspiration and expiration, focusing on the correlation between Doppler-measured velocity and data from mechanical ventilators or spirometers. The study includes both healthy individuals and patients with lung diseases to better understand the dynamics of lung sliding. This approach seeks to enhance the diagnostic capabilities of lung ultrasound, particularly in emergency settings.
Who should consider this trial
Good fit: Ideal candidates for this study are adults aged 18 and older who can provide informed consent.
Not a fit: Patients undergoing major thoracic surgery or with a history of recurrent pneumothorax may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could improve the accuracy of lung assessments and aid in the diagnosis of respiratory conditions.
How similar studies have performed: While there have been pilot studies using pulmonary Doppler in healthy individuals, the specific use of pulsed Doppler for measuring lung parenchyma sliding is novel and has not been extensively tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age \>= 18 years * Acquisition of Informed Consent Exclusion Criteria: * Patients admitted to undergo major thoracic surgery. * Remote pathological history positive for recurrent PNX (≥ 2), pleural thalking or pleurodesis * Patients presenting with absolute and relative contraindications to spirometry for1 and 2a patients ie: recent myocardial infarction (within the past 3 months) or unstable angina hemoptysis thoracic aortic aneurysm
Where this trial is running
Bologna and 1 other locations
- IRCCS Azienda Ospedaliero-Universitaria di Bologna Policlinico di Sant'Orsola, UOC Anestesiologia e Terapia Intensiva Polivalente — Bologna, Italy (Recruiting)
- IRCCS Azienda Ospedaliero-Universitaria di Bologna, Policlinico di Sant'Orsola, UO Pneumologia — Bologna, Italy (Recruiting)
Study contacts
- Principal investigator: Tommaso Tonetti, MD — IRCCS Azienda Ospedaliero-Universitaria di Bologna - Anestesiologia e Terapia Intensiva Polivalente
- Study coordinator: Tommaso Tonetti, MD
- Email: tommaso.tonetti@unibo.it
- Phone: 051 214 4309
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.