Measuring eye accommodation response under different conditions
Refractive Status and Accommodation Response Under Different Experimental Conditions.
This study is testing new ways to measure how well the eye can focus on close objects in healthy adults aged 18 to 40 to see if it can improve eye exams.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 55 (estimated) |
| Ages | 18 Years to 40 Years |
| Sex | All |
| Sponsor | Essilor International Industry-sponsored |
| Locations | 1 site (Créteil) |
| Trial ID | NCT06331780 on ClinicalTrials.gov |
What this trial studies
This clinical investigation aims to explore new methods for measuring the accommodative response of the eye, particularly focusing on the dynamics and amplitude of this response. The study will involve healthy volunteers aged 18 to 40 who have recently visited an ophthalmologist and do not have any visual or cognitive impairments. Various parameters will be manipulated during the measurement process, including visual acuity and different accommodation measurement techniques. The goal is to improve the reliability of near vision assessments using auto-refractors, which are commonly used by eye care professionals.
Who should consider this trial
Good fit: Ideal candidates for this study are healthy volunteers aged 18 to 40 who have had an eye examination within the last year.
Not a fit: Patients with significant refractive errors or astigmatism beyond specified limits may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to more accurate assessments of near vision, benefiting patients with accommodation disorders.
How similar studies have performed: While this approach is exploratory, previous studies have indicated that there are challenges in measuring accommodative response accurately, suggesting a need for improved methodologies.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Volunteer: man or woman from 18 to 40 years old, * Subject declares that his last visit to an ophthalmologist was less than 12 months ago, * Subjects without a reported pathology, deficit or disorder that can interfere with visual or cognitive functions, * Subjects, healthy volunteers who have been fully informed of the investigation and signed the informed consent form of the investigation, * Subjects available for the investigation visits (at least 2 hours), * Subjects able to appoint a visit in the investigator's site, * Subjects able to read and understand the protocol (in French), follow the instructions, and give their informed consent approval. Exclusion Criteria: * Subjects with spherical equivalent wearing compensation (or fully compensate by contact lenses) ranging out from -3.00 to + 3.00 Dioptres in both eyes, * Subjects with an astigmatism wearing compensation (or fully compensate by contact lenses) more than 1.00 Dioptres (\>1,00DC) in both eyes, * Subjects with a best compensated monocular VA \< 8/10 (\>0.1logMAR), * Persons subject to a legal protection measure (guardianship, curatorship, safeguard of justice, etc.) or unable to express their consent (see Article L 1121-8 of the CSP) * Persons deprived of their liberty by judicial or administrative decision and persons hospitalised without their consent (article L1121-6 of the CSP), * Subjects under exclusion period from another investigation, * Women pregnant or breastfeeding; (Article L1121-5), * Subjects with a reported neurologic disorder, particularly epileptic or sensory motor troubles, * Subjects with implanted electronic medical device such as (pacemaker or hearing aid), * Subjects with a reported severe ocular disease leading to a visual field decrease, VA deficiency or glare sensitivity, * Subjects with monophtalmia * Subjects who had ocular surgeries (including aphakia or pseudophakia (intraocular lenses), refractive surgery or trauma), * Subjects who are ESSILOR INTERNATIONAL employees * Subjects who are not affiliated to a social security scheme or are beneficiaries of such a scheme (article L1121-8-1 of the CSP). * Subject with fixation disorder: impossibility to maintain fixation on visual target. * Subjects who cannot stay comfortable during the tests (e.g. with neck pain ...). * Pupil abnormality (unusual shape, size \<3mm)
Where this trial is running
Créteil
- Essilor International - Ci&T 2 — Créteil, France (Recruiting)
Study contacts
- Principal investigator: Jérôme Gillet — ESSILOR INTERNATIONAL - Division Instruments
- Study coordinator: Thierry Laloux
- Email: lalouxt@essilor.fr
- Phone: +33 (1) 55 96 54 05
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.