Clinical trial Recruiting at 1 site Observational Ages 18 to 99

Measuring esophageal function and swallowing difficulties

Official title: Esophageal Impedance and Manometry Measurements and Dysphagia Symptom Scoring

Run by Indiana University · NCT04503785 · Data updated 2026-11-12

This study is trying to see how two different tests for swallowing problems work in patients with known esophageal issues to better understand their symptoms.

Quick facts

Study typeObservational
Ages18 Years to 99 Years
SexAll
Enrollment1000 (estimated)
SponsorIndiana University
Academic / other
Locations1 site (Indianapolis, Indiana)
StatusRecruiting
StartedJanuary 17, 2017
Main results expectedDecember 31, 2026
Study endsDecember 31, 2027
Registry record updatedJune 16, 2026
Trial IDNCT04503785 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are adults presenting to the GI Motility Lab at Indiana University Hospital for esophageal manometry-impedance and/or EndoFLIP.

Probably not a fit

Patients under 18 years old or those unable to communicate verbally with staff will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to compare esophageal manometry measurements and EndoFLIP Balloon measurements in patients experiencing dysphagia, or difficulty swallowing. It focuses on patients with known esophageal diagnoses who are referred to the GI Motility Lab at Indiana University Hospital. The study seeks to establish a registry that correlates the results of these diagnostic tests with clinical symptoms, enhancing the understanding of non-obstructive dysphagia. Both tests used in this study are FDA-approved and currently utilized in clinical practice.

Why it matters

Potential benefit: If successful, this study could improve the diagnosis and management of dysphagia, leading to better treatment options for patients.

How similar studies have gone: While the use of manometry and EndoFLIP is established, the correlation between these tests and clinical symptoms in dysphagia has not been clearly defined, making this approach novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* All patients who presented to GI Motility Lab at IU University Hospital for esophageal manometry-impedance and/or EndoFLIP

Exclusion Criteria:

* Age \<18 yrs old
* Unable to communicate verbally with the staff

Where it's running

  • Indiana University Health University Hospital
    Indianapolis, Indiana, United States
    Recruiting

Study contacts

  • Principal investigator: John M Wo, MD — Indiana University
  • Study coordinator: Lainna Cohen
  • Email: larcohen@iu.edu

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.