Measuring esophageal function and swallowing difficulties
Official title: Esophageal Impedance and Manometry Measurements and Dysphagia Symptom Scoring
Run by Indiana University · NCT04503785 · Data updated 2026-11-12
This study is trying to see how two different tests for swallowing problems work in patients with known esophageal issues to better understand their symptoms.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 99 Years |
| Sex | All |
| Enrollment | 1000 (estimated) |
| Sponsor | Indiana University Academic / other |
| Locations | 1 site (Indianapolis, Indiana) |
| Status | Recruiting |
| Started | January 17, 2017 |
| Main results expected | December 31, 2026 |
| Study ends | December 31, 2027 |
| Registry record updated | June 16, 2026 |
| Trial ID | NCT04503785 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are adults presenting to the GI Motility Lab at Indiana University Hospital for esophageal manometry-impedance and/or EndoFLIP.
✕Probably not a fit
Patients under 18 years old or those unable to communicate verbally with staff will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to compare esophageal manometry measurements and EndoFLIP Balloon measurements in patients experiencing dysphagia, or difficulty swallowing. It focuses on patients with known esophageal diagnoses who are referred to the GI Motility Lab at Indiana University Hospital. The study seeks to establish a registry that correlates the results of these diagnostic tests with clinical symptoms, enhancing the understanding of non-obstructive dysphagia. Both tests used in this study are FDA-approved and currently utilized in clinical practice.
Why it matters
Potential benefit: If successful, this study could improve the diagnosis and management of dysphagia, leading to better treatment options for patients.
How similar studies have gone: While the use of manometry and EndoFLIP is established, the correlation between these tests and clinical symptoms in dysphagia has not been clearly defined, making this approach novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * All patients who presented to GI Motility Lab at IU University Hospital for esophageal manometry-impedance and/or EndoFLIP Exclusion Criteria: * Age \<18 yrs old * Unable to communicate verbally with the staff
Where it's running
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Indiana University Health University Hospital
Indianapolis, Indiana, United States Recruiting
Study contacts
- Principal investigator: John M Wo, MD — Indiana University
- Study coordinator: Lainna Cohen
- Email: larcohen@iu.edu
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.