Measuring Diaphragm Thickness in Adolescents with Chest Deformities
Ultrasonographic Measurement of Diaphragmatic Thickness in Adolescents With Pectus Deformity: Is it an Early Predictor of Respiratory Dysfunction?
This study is testing how thick the diaphragm is in teenagers with chest deformities to see if it can help predict breathing problems before they show any symptoms.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 40 (estimated) |
| Ages | 10 Years to 18 Years |
| Sex | All |
| Sponsor | Gaziosmanpasa Research and Education Hospital Government |
| Locations | 1 site (Istanbul, Gaziosmanpasa) |
| Trial ID | NCT06392984 on ClinicalTrials.gov |
What this trial studies
This observational study aims to measure diaphragmatic thickness in adolescents aged 10-18 with pectus deformities, such as pectus excavatum and pectus carinatum. The researchers will utilize ultrasonography to assess diaphragm function and thickness, investigating its potential as an early predictor of respiratory disorders in patients who may not exhibit clinical symptoms. The study will include pulmonary function tests to correlate diaphragm measurements with respiratory health. By focusing on this demographic, the study seeks to enhance understanding of how pectus deformities impact respiratory function.
Who should consider this trial
Good fit: Ideal candidates are adolescents aged 10-18 with increased thoracic kyphosis and the ability to cooperate with spirometry.
Not a fit: Patients with congenital anomalies, neuromuscular diseases, or existing respiratory conditions may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide early indicators of respiratory issues in adolescents with pectus deformities, leading to timely interventions.
How similar studies have performed: While the use of ultrasonography for diaphragm assessment is gaining traction, this specific approach in adolescents with pectus deformities is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Increased thoracal kyphosis (thoracic hyperkyphosis) * Being between the ages of 10-18 * Patients who can cooperate with spirometry. Exclusion Criteria: * Congenital spinal, costal and diaphragmatic anomalies * Neuromuscular disease * Respiratory system diseases that affect lung functions * Patients who cannot cooperate with spirometry. * Having surgery to the chest wall or spine
Where this trial is running
Istanbul, Gaziosmanpasa
- Zeynel Karakullukcuoglu, — Istanbul, Gaziosmanpasa, Turkey (Recruiting)
Study contacts
- Study coordinator: Zeynel Karakullukcuoglu, MD
- Email: zeynel@uludag.edu.tr
- Phone: +90 541 216 61 16
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.