Measuring diaphragm loading during inspiratory muscle training

Measurement of the Diaphragm Loading During the Training With a Inspiratory Muscle Trainer Device

Observational Clínica Basilea · NCT05542069

This study is trying to see how different breathing exercises with a special device affect the diaphragm in healthy adults.

Quick facts

Study typeObservational
Enrollment10 (estimated)
Ages18 Years and up
SexAll
SponsorClínica Basilea Academic / other
Locations1 site (Buenos Aires)
Trial IDNCT05542069 on ClinicalTrials.gov

What this trial studies

This observational study aims to assess the diaphragm loading in healthy adults while using an inspiratory muscle training (IMT) device. Ten healthy volunteers will be monitored using esophageal and gastric manometry as they perform breathing exercises with varying resistive loads. The study will analyze the relationship between gastric pressure and transdiaphragmatic pressure to determine diaphragm involvement during the training. Each subject will undergo multiple sessions with randomized loads to gather comprehensive data on diaphragm function.

Who should consider this trial

Good fit: Ideal candidates for this study are healthy adults over the age of 18 without any respiratory or esophageal conditions.

Not a fit: Patients with anticoagulation therapy, esophageal lesions, airway lesions, or spirometry alterations may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could enhance our understanding of diaphragm mechanics during IMT, potentially leading to improved training protocols for respiratory health.

How similar studies have performed: While diaphragm loading during IMT has been studied, this specific approach using manometry to quantify diaphragm involvement is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* older than 18 years
* healthy subjects

Exclusion Criteria:

* without anticoagulation
* without esophageal lesions
* without airway lesions
* without spirometry alterations

Where this trial is running

Buenos Aires

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Sports Physical Therapy
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.