Measuring chest wall movement after esophageal surgery
Changes in Respiratory Function and Chest Wall Movement Following Oesophagectomy
This study is testing how well different types of esophageal surgery affect chest movement and breathing in patients to help improve recovery after surgery.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 100 (estimated) |
| Ages | 18 Years to 90 Years |
| Sex | All |
| Sponsor | Imperial College London Academic / other |
| Locations | 1 site (London) |
| Trial ID | NCT03835273 on ClinicalTrials.gov |
What this trial studies
This observational study aims to assess chest wall movement in patients who have undergone esophagectomy for esophageal cancer, comparing those who had open surgery versus minimally invasive techniques. It involves 50 healthy volunteers and 100 patients treated over a year ago, utilizing a 3D motion capture system and wearable measurement devices to quantify chest expansion and lung capacity. The study will also gather data on pulmonary function and health-related quality of life to evaluate the effectiveness of tailored physiotherapy interventions. The goal is to establish reliable measurement methods for chest wall movement and improve post-surgical recovery.
Who should consider this trial
Good fit: Ideal candidates include patients who have undergone esophagectomy for esophageal cancer more than a year ago and healthy volunteers without prior upper gastrointestinal surgery.
Not a fit: Patients with ongoing postoperative complications, cancer recurrence, or those unable to provide informed consent will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved recovery protocols and tailored physiotherapy for patients after esophagectomy, enhancing respiratory function and quality of life.
How similar studies have performed: While similar studies have explored minimally invasive techniques and recovery protocols, this specific approach using 3D motion capture for chest wall measurement is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Exposure group: 1. Patients treated more than a year ago with oesophagectomy for oesophageal cancer, by an open approach. 2. Patients able to understand and retain the information provided, thereby being able to give informed consent for inclusion in this study. * Control group: 1. Healthy volunteers with no underlying respiratory disease and no history of upper gastrointestinal surgery. 2. Individuals able to understand and retain the information provided, thereby being able to give informed consent for inclusion in this study. Exclusion Criteria: * Any participant who lacks capacity or is unable to provide informed consent. * Any participant younger than 18 or older than 90 years of age. * Any patient with evidence of cancer recurrence or on-going postoperative complication at more than one year following surgery for oesophageal cancer. * Any pregnant participant. * unable to or excluded from performing spirometry or respiratory muscle strength testing (non-invasive testing)
Where this trial is running
London
- Charing Cross Hospital — London, United Kingdom (Recruiting)
Study contacts
- Principal investigator: Sheraz R Markar, Dr — Imperial College London
- Study coordinator: Sheraz R Markar, Dr
- Email: s.markar@imperial.ac.uk
- Phone: +44203312 2125
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.