Measuring changes in lung artery pressure using a non-invasive method in ICU patients
Non-Invasive Measurements of Changes in Pulmonary Artery Pressure in Intensive Care Unit Patients Using Electrical Impedance Tomography - A Feasibility Study (PAP-EIT Study)
This study is testing if a new non-invasive method called electrical impedance tomography can safely and accurately measure lung artery pressure in critically ill patients in the ICU.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 28 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Insel Gruppe AG, University Hospital Bern Academic / other |
| Locations | 1 site (Bern) |
| Trial ID | NCT06544148 on ClinicalTrials.gov |
What this trial studies
This study evaluates the feasibility of using electrical impedance tomography (EIT) to monitor changes in pulmonary artery pressure (PAP) in critically ill patients. It compares the non-invasive EIT measurements with the invasive gold-standard method of PAP measurement using a pulmonary artery catheter. The goal is to determine if EIT can provide reliable data on PAP changes without the risks associated with invasive procedures. The study focuses on intubated ICU patients who require PAP monitoring.
Who should consider this trial
Good fit: Ideal candidates are intubated patients aged 18 and older in the ICU who require monitoring of pulmonary artery pressure.
Not a fit: Patients with implanted thoracic electronic devices, open lung injuries, or certain thoracic conditions may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could provide a safer, non-invasive method for monitoring pulmonary artery pressure in critically ill patients.
How similar studies have performed: While this approach is innovative, similar studies using non-invasive methods for monitoring cardiovascular parameters have shown promise, suggesting potential for success.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion criteria: * Age ≥ 18-year-old. * Intubated patients in the ICU with clinical decision to monitor PAP and cardiac output using a PAC. Exclusion criteria: * Patients with implanted or external thoracic electronic devices (e.g., pacemaker) or thoracic metal implants. * Known pregnancy or lactating patients. * Open lung injuries or pneumothorax. * Open wounds, drainages, burns or rashes of the upper thorax. * Estimated thoracic perimeter smaller than 66 cm or larger than 134 cm. * Known allergies to wound dressings or adhesives (e.g., gel electrodes)
Where this trial is running
Bern
- Inselspital Bern, Universitätsklinik für Intensivmedizin — Bern, Switzerland (Recruiting)
Study contacts
- Principal investigator: Kaspar F Bachmann, MD — Department of Intensive Care Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland
- Study coordinator: Kaspar F Bachmann, MD
- Email: kaspar.bachmann@faculty.unibe.ch
- Phone: +41 31 632 21 11
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.