Measuring carotenoid levels in the eye and skin
Macular Pigment Measurements in Eye & Other Tissues
This study is testing how nutrition affects eye health by measuring carotenoid levels in the eye and skin of patients at the Moran Eye Center to see if these nutrients can help protect against vision loss.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 10000 (estimated) |
| Ages | 7 Years and up |
| Sex | All |
| Sponsor | University of Utah Academic / other |
| Locations | 1 site (Salt Lake City, Utah) |
| Trial ID | NCT03022773 on ClinicalTrials.gov |
What this trial studies
This study aims to explore the impact of nutrition on eye health by measuring carotenoid concentrations in the human eye and skin tissues. It will validate non-invasive methods for assessing these carotenoid levels, specifically lutein and zeaxanthin, which are believed to protect against age-related macular degeneration. Additionally, the study will correlate these measurements with blood levels of carotenoids in a subset of participants. The research is conducted at the Moran Eye Center, focusing on patients undergoing routine ophthalmology examinations.
Who should consider this trial
Good fit: Ideal candidates include individuals aged 7 and older undergoing routine eye examinations, particularly those with adult vitelliform dystrophy.
Not a fit: Patients under the age of 7 will not benefit from this study as they are excluded from participation.
Why it matters
Potential benefit: If successful, this study could enhance understanding of dietary influences on eye health and potentially reduce the risk of vision loss.
How similar studies have performed: Epidemiological studies have shown associations between carotenoid intake and reduced vision loss, suggesting that this approach has a foundation in previous research.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Any patient age 7 or older, undergoing routine dilated ophthalmology examinations at the Moran Eye Center will be eligible to participate. * Patients with adult vitelliform dystrophy. (This condition initially presents in adulthood as bilateral subtle and often asymptomatic macular lesions, which are often misdiagnosed as early age-related macular degeneration (AMD)). Exclusion Criteria: * Patients under age 7 will not be eligible to participate.
Where this trial is running
Salt Lake City, Utah
- University of Utah John A. Moran Eye Center — Salt Lake City, Utah, United States (Recruiting)
Study contacts
- Principal investigator: Paul Bernstein, MD, PhD — University of Utah Moran Eye Center
- Study coordinator: Paul S. Bernstein, MD, PhD
- Email: Paul.Bernstein@hsc.utah.edu
- Phone: 801-581-4069
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.