Measuring breathing effort in patients with idiopathic pulmonary fibrosis
Inspiratory Effort Assessed Through Nasal Pressure Measurement in Patients With Idiopathic Pulmonary Fibrosis
This study is trying to see how hard people with idiopathic pulmonary fibrosis have to work to breathe, to better understand how the disease is progressing.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 100 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University of Modena and Reggio Emilia Academic / other |
| Locations | 1 site (Modena) |
| Trial ID | NCT05310669 on ClinicalTrials.gov |
What this trial studies
This observational study focuses on patients diagnosed with idiopathic pulmonary fibrosis (IPF) to assess their inspiratory effort through nasal pressure measurements. The research aims to better understand the progression of lung damage in IPF, a condition characterized by severe respiratory failure and a median survival of three years post-diagnosis. By evaluating the inspiratory effort, the study seeks to identify potential correlations with disease progression and acute exacerbations. Participants will undergo radiological evaluations to confirm their diagnosis and suitability for the study.
Who should consider this trial
Good fit: Ideal candidates are adults diagnosed with idiopathic pulmonary fibrosis exhibiting a usual interstitial pneumonia pattern.
Not a fit: Patients with conditions such as COPD, neuromuscular diseases, or those experiencing acute exacerbations of IPF may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance understanding of IPF progression and improve management strategies for patients.
How similar studies have performed: While there have been studies on IPF and its management, this specific approach using nasal pressure measurement is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: Patients treated in Center for Rare diseases of Azienda Ospedaliero-Universitaria Policlinico di Modena will be considered eligible if satisfying the following inclusion criteria: * Patient with IPF and UIP pattern * Need for radiological evaluation through HRCT Exclusione criteria * Age below 18 * Pregnancy * Inability to sign informed consent * COPD * Neuromuscular diseases * Evidence of IPF acute exacerbation
Where this trial is running
Modena
- Azienda Ospedaliero Universitaria Policlinico di Modena — Modena, Italy (Recruiting)
Study contacts
- Study coordinator: Roberto Tonelli, MD
- Email: roberto.tonelli@unimore.it
- Phone: +390594225934
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.