Measuring brain connectivity in stroke patients using high-density electroencephalography
Brain Connectivity Measured With High-density Electroencephalography: a Novel Neurodiagnostic Tool for Stroke
This study is testing a new way to measure brain activity in stroke patients to see how their brain connections change and help create better rehab plans for them.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 170 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | IRCCS San Camillo, Venezia, Italy Academic / other |
| Locations | 1 site (Venice) |
| Trial ID | NCT06298097 on ClinicalTrials.gov |
What this trial studies
This study aims to develop and implement high-density electroencephalography (hdEEG) techniques to assess functional connectivity in stroke patients. By examining how neural synchronization in brain networks is altered after a stroke, the researchers hope to identify prognostic factors that can inform individualized rehabilitation protocols. The project will involve recruiting 125 stroke patients and 45 healthy participants to validate these methods. Ultimately, the goal is to enable bedside neurodiagnostic assessments for stroke and potentially other conditions.
Who should consider this trial
Good fit: Ideal candidates for this study are stroke patients with either right or left hemisphere damage and no psychiatric comorbidities.
Not a fit: Patients with psychiatric disorders or those who cannot comply with magnetic resonance imaging requirements may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could lead to improved rehabilitation strategies tailored to individual stroke patients based on their unique neural connectivity profiles.
How similar studies have performed: While the use of hdEEG in healthy individuals has shown promise, this application in stroke patients is novel and has not been widely tested.
Eligibility criteria
Show full inclusion / exclusion criteria
In this study 125 stroke patients and 45 healthy participants will be recruited at the Institute for Research and Healthcare with a Scientific Character (IRCCS) San Camillo hospital. Inclusion Criteria (patients): * right or left hemisphere damage * unilateral stroke * compliance with magnetic resonance imaging (e.g., no claustrophobia) Inclusion Criteria (healthy participants): • compliance with magnetic resonance imaging (e.g., no claustrophobia) Exclusion Criteria (both patients and healthy participants): • no comorbidities with psychiatric disorders
Where this trial is running
Venice
- IRCCS San Camillo Hospital — Venice, Italy (Recruiting)
Study contacts
- Study coordinator: Dante Mantini
- Email: dante.mantini@hsancamillo.it
- Phone: +39 0412207594
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.