Measuring abdominal aorta diameter in women 50 and older
Official title: Studio Osservazionale Prospettico Multicentrico nazionAle Nel Sesso Femminile peR la valutaziOne Del DIametro Dell'aorTa addominalE - A National, Multicenter, Prospective Observational Study in Females to Assess Abdominal Aortic Diameter
Run by Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico · NCT07487961 · Data updated 2026-11-12
This project will measure abdominal aorta and common iliac artery sizes and collect reproductive and health history from women aged 50 and older to define typical diameters and identify female-specific risk factors for aortic disease.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 50 Years and up |
| Sex | Women only |
| Enrollment | 652 (estimated) |
| Sponsor | Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico Academic / other |
| Locations | 1 site (Milan) |
| Status | Recruiting |
| Started | September 29, 2025 |
| Main results expected | July 30, 2027 |
| Study ends | July 30, 2027 |
| Registry record updated | March 27, 2026 |
| Trial ID | NCT07487961 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Women aged 50 years or older who can provide informed consent and who have no prior diagnosis of thoracic or abdominal aortic aneurysm and no prior aortic surgery are ideal candidates.
✕Probably not a fit
Women under 50, those with a prior aortic aneurysm diagnosis or prior open or endovascular aortic surgery, and individuals unable to consent are excluded and unlikely to benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
Women aged 50 and older without prior aortic aneurysm or aortic surgery will be enrolled and undergo ultrasound measurement of the abdominal aorta and common iliac arteries using standard perpendicular probe placement with inner-to-inner and outer-to-outer caliper recordings. Measurements will include antero-posterior and lateral diameters and documentation of thrombus or calcification. Investigators will also collect demographic, pathophysiological, and reproductive history data including menarche, pregnancy/infertility, and menopause. The primary goal is to define ultrasound reference diameters in the female population and secondarily to identify sex-specific risk factors for abdominal aortic disease.
Why it matters
Potential benefit: If successful, this work could establish female-specific aortic diameter reference ranges and help identify women at higher risk of aneurysm or rupture, improving screening and treatment timing.
How similar studies have gone: Standard ultrasound measurement techniques are well established, but dedicated studies defining female-specific aortic diameter norms are limited, so this approach addresses a relatively understudied area.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * female sex * ≥ 50 YO Exclusion Criteria: * \< 50 years * Previous diagnosis of abdominal/thoracic aneurysm disease * Subjects who have previously undergone surgery (both open and endovascular) on the thoracic and/or abdominal aorta * Presence of mental disability and/or inability to sign informed consent
Where it's running
-
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
Milan, Italy Recruiting
Study contacts
- Study coordinator: Chiara Lomazzi, Md
- Email: chiara.lomazzi@policlinico.mi.it
- Phone: +390255036670
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Digital Twin and ML-Driven Modeling of TEVAR Procedures
Aims to collect anonymized patient data and CT scans from people undergoing TEVAR to build a digital twin that can simulate results and help doctors choose devices and plan procedures.
-
Retreatment with the Nectero EAST System for abdominal aortic aneurysm
This will try retreatment with the Nectero EAST System to repair infrarenal abdominal aortic aneurysms in adults who previously received the device under the initial protocol.
-
Evaluation of clinical results for patients with aorta and peripheral artery revascularization
This study looks at the long-term health results of around 6,000 patients who have had surgery to improve blood flow in their aorta and legs.
-
Treatment for Thoracic Aortic Aneurysms and Valve Conditions
This study is trying to see if surgery is the right choice for patients with slightly enlarged aortas and specific heart valve conditions, to help improve treatment guidelines for thoracic aortic aneurysms.
-
Comparing surgery and monitoring for ascending aortic aneurysms
This study tests whether early surgery or careful monitoring is better for people aged 18 to 79 with asymptomatic ascending aortic aneurysms that are between 5.0 cm and 5.4 cm.
-
Castor and Cratos Branched Aortic Grafts Registry for Thoracic Aortic Pathologies
This European registry collects real-world data to see how Castor and Cratos branched stent grafts perform in adults with thoracic aortic diseases.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.