Maxillary sinus lift using a 1:1 mix of your own bone and bovine bone versus bovine bone alone
Official title: Radiographic and Histomorphometric Assessment for Maxillary Sinus Floor Elevation and Augmentation Using A Mixture of 1:1 Autogenous Bone With Deproteinized Bovine Bone Particulate Versus Deproteinized Bovine Bone Particulate: A Randomized Clinical Trial
Run by Cairo University · NCT07177495 · Data updated 2026-11-12
This test sees if mixing a patient's own bone with deproteinized bovine bone makes better grafted bone for sinus lifts than using bovine bone alone in adults with very little upper back jaw bone.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 30 Years and up |
| Sex | All |
| Enrollment | 26 (estimated) |
| Sponsor | Cairo University Academic / other |
| Locations | 1 site (Cairo, Giza Governorate) |
| Status | Recruiting |
| Started | April 10, 2025 |
| Main results expected | February 10, 2026 |
| Study ends | March 10, 2026 |
| Registry record updated | September 17, 2025 |
| Trial ID | NCT07177495 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults over 30 with an atrophied posterior maxilla and residual bone height under 5 mm, adequate inter-arch space, and the ability to comply with follow-up visits are ideal candidates.
✕Probably not a fit
Patients with sinus pathology, heavy smoking (>10 cigarettes/day), parafunctional habits, uncontrolled systemic disease, poor oral hygiene, or significant psychiatric instability are unlikely to benefit or be eligible.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
Before surgery patients receive CBCT imaging to map sinus anatomy and rule out sinus disease. Participants are placed into two groups that undergo an open lateral window sinus lift procedure performed by one experienced surgeon, with the Schneiderian membrane elevated and graft material placed into the sinus. One group receives a 1:1 mixture of autogenous bone and deproteinized bovine bone particulate while the other group receives deproteinized bovine bone particulate alone, and a collagen membrane is placed over the graft before flap closure. Implant placement and a core biopsy are performed later as part of the follow-up to measure new bone formation and graft integration.
Why it matters
Potential benefit: If successful, the mixed autogenous/bovine graft could produce more new bone and stronger support for dental implants, potentially reducing the need for additional grafting.
How similar studies have gone: Previous clinical reports using mixtures of autogenous and deproteinized bovine bone have shown improved new bone formation in some cases, but results vary and are not uniformly conclusive.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * • Patients of both genders requiring implants placement in atrophied posterior maxilla with residual bone height less than 5mm . * Patients of age older than 30 years old. * Patients with adequate Inter-arch space. * Patients who were willing and fully capable to comply with the study protocol. Exclusion Criteria: * • Patients suffering from any sinus pathosis * Heavy smokers (\> than 10 cigarettes a day) * Patients with parafunctional habits * Patients with uncontrolled systemic diseases. * Patients with poor oral hygiene * Patients with mental instabilities or psychic patients
Where it's running
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faculty of oral and dental medicine, Cairo university
Cairo, Giza Governorate, Egypt Recruiting
Study contacts
- Study coordinator: Merna Hamdy Abdelhamid, BSc
- Email: Merna-hamdy@dentistry.cu.edu.eg
- Phone: +201060696920
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Adding erythropoietin to albumin platelet-rich fibrin for transcrestal sinus lift with dental implant placement
This will see if adding erythropoietin to albumin platelet-rich fibrin during transcrestal sinus lifts helps people with reduced upper jaw bone who are getting dental implants.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.