Maxillary expansion to treat crowding in children's teeth
Official title: Interceptive Maxillary Expansion to Relief Anterior Crowding in the Mixed Dentition: a Longitudinal, Randomized Controlled Trial
Run by Region Örebro County · NCT06187337 · Data updated 2026-11-12
This study is testing if using a special device to widen the upper jaw early can help kids aged six to nine with crowded teeth feel better and have healthier smiles compared to waiting until they're older for treatment.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 6 Years to 16 Years |
| Sex | All |
| Enrollment | 60 (estimated) |
| Sponsor | Region Örebro County Academic / other |
| Locations | 4 sites (Coppito and 3 other locations) |
| Status | Recruiting |
| Started | December 20, 2021 |
| Main results expected | January 31, 2027 |
| Study ends | January 31, 2028 |
| Registry record updated | July 18, 2025 |
| Trial ID | NCT06187337 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are healthy children aged six to nine with at least six millimeters of crowding in their upper front teeth.
✕Probably not a fit
Patients with skeletal asymmetries, previous orthodontic treatment, or severe crowding in the lower arch may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This clinical trial aims to compare the effectiveness of early maxillary expansion versus treatment in the permanent dentition for children aged six to nine with severe anterior crowding of the upper teeth. Participants will be randomly assigned to either an experimental group receiving a maxillary expansion appliance or a control group. The study will evaluate the degree of crowding, oral health-related quality of life, and the cost-effectiveness of early treatment over a five-year follow-up period. Advanced imaging techniques will be utilized to assess dental arch development and crowding metrics.
Why it matters
Potential benefit: If successful, this approach could lead to improved dental health and quality of life for children with anterior crowding.
How similar studies have gone: Previous studies on early orthodontic interventions have shown promising results, suggesting that this approach may be effective.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Healthy subjects without sucking habits * Permanent maxillary central incisors and first permanent molars fully erupted. DS1M1. * No severe crowding or protrusion in the lower arch considering the Leeway space and normal development of the arch. * Permanent first molar in normal transversal relation. * Crowding of the maxillary incisors with the lateral incisor just erupting ectopically or not yet emerged through the gingiva. * Crowding greater than or equal to 6 millimeters between the upper deciduous canines. Exclusion Criteria: * Skeletal asymmetries, anomalies and syndromes. * Previous orthodontic treatment
Where it's running
-
Postgraduate School of Orthodontics, University of L'Aquila
Coppito, Italy Recruiting -
Universita Degli Studi Di Milano
Milan, Italy Recruiting -
The Institute for Postgraduate Dental Education in Jönköping
Jönköping, Sweden Recruiting -
Emil Östlund
Örebro, Sweden Recruiting
Study contacts
- Study coordinator: Emil Östlund, DDS
- Email: emil.ostlund@regionorebrolan.se
- Phone: +46196024045
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.