Maxillary expansion to treat crowding in children's teeth
Interceptive Maxillary Expansion to Relief Anterior Crowding in the Mixed Dentition: a Longitudinal, Randomized Controlled Trial
NA · Region Örebro County · NCT06187337
This study is testing if using a special device to widen the upper jaw early can help kids aged six to nine with crowded teeth feel better and have healthier smiles compared to waiting until they're older for treatment.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 60 (estimated) |
| Ages | 6 Years to 16 Years |
| Sex | All |
| Sponsor | Region Örebro County (other) |
| Locations | 4 sites (Coppito and 3 other locations) |
| Trial ID | NCT06187337 on ClinicalTrials.gov |
What this trial studies
This clinical trial aims to compare the effectiveness of early maxillary expansion versus treatment in the permanent dentition for children aged six to nine with severe anterior crowding of the upper teeth. Participants will be randomly assigned to either an experimental group receiving a maxillary expansion appliance or a control group. The study will evaluate the degree of crowding, oral health-related quality of life, and the cost-effectiveness of early treatment over a five-year follow-up period. Advanced imaging techniques will be utilized to assess dental arch development and crowding metrics.
Who should consider this trial
Good fit: Ideal candidates are healthy children aged six to nine with at least six millimeters of crowding in their upper front teeth.
Not a fit: Patients with skeletal asymmetries, previous orthodontic treatment, or severe crowding in the lower arch may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could lead to improved dental health and quality of life for children with anterior crowding.
How similar studies have performed: Previous studies on early orthodontic interventions have shown promising results, suggesting that this approach may be effective.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Healthy subjects without sucking habits * Permanent maxillary central incisors and first permanent molars fully erupted. DS1M1. * No severe crowding or protrusion in the lower arch considering the Leeway space and normal development of the arch. * Permanent first molar in normal transversal relation. * Crowding of the maxillary incisors with the lateral incisor just erupting ectopically or not yet emerged through the gingiva. * Crowding greater than or equal to 6 millimeters between the upper deciduous canines. Exclusion Criteria: * Skeletal asymmetries, anomalies and syndromes. * Previous orthodontic treatment
Where this trial is running
Coppito and 3 other locations
- Postgraduate School of Orthodontics, University of L'Aquila — Coppito, Italy (RECRUITING)
- Universita Degli Studi Di Milano — Milan, Italy (RECRUITING)
- The Institute for Postgraduate Dental Education in Jönköping — Jönköping, Sweden (RECRUITING)
- Emil Östlund — Örebro, Sweden (RECRUITING)
Study contacts
- Study coordinator: Emil Östlund, DDS
- Email: emil.ostlund@regionorebrolan.se
- Phone: +46196024045
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Crowding of Anterior Maxillary Teeth, Orthodontics, Interceptive, Orthodontics, Corrective, Palatal Expansion Technique