Markers of Caloric Balance
Official title: Caloric Balance Markers (CaBooM) Study
Run by Institute for Systems Biology · NCT07141537 · Data updated 2026-11-12
This project will try to find biological markers that show how calories eaten compare to calories burned in adults.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 400 (estimated) |
| Sponsor | Institute for Systems Biology Academic / other |
| Locations | 1 site (Seattle, Washington) |
| Status | Recruiting |
| Started | August 27, 2025 |
| Main results expected | August 31, 2033 |
| Study ends | August 31, 2033 |
| Registry record updated | September 3, 2025 |
| Trial ID | NCT07141537 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults aged 18 or older who can travel to the Institute for Systems Biology in Seattle, speak English, and provide informed consent are ideal candidates.
✕Probably not a fit
People under 18, prisoners, those unable to provide informed consent, or those who cannot travel to Seattle are not eligible and are unlikely to benefit from participating.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
CaBooM is an observational project that seeks to identify and characterize biomarkers reflecting the relationship between energy intake and energy expenditure. Adult participants will attend visits at the Institute for Systems Biology in Seattle and provide biologic samples and physiologic measurements to link signals of intake and expenditure. The study combines clinical measurements with laboratory analyses to search for consistent markers of caloric balance. Results are intended to inform future diagnostic tools or targeted interventions for metabolic health.
Why it matters
Potential benefit: If successful, this work could enable tests that more accurately measure energy balance and help personalize nutrition or weight-management strategies.
How similar studies have gone: Related observational biomarker studies have identified candidate metabolic signals but few have produced validated, widely adopted markers of whole-body caloric balance, so this approach builds on partial prior work and remains exploratory.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * \> 18 years of age * Able to travel to ISB for study visits. * Able to read and communicate in English. Exclusion Criteria: * \- Unable to provide informed consent. * Is a prisoner.
Where it's running
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Institute for Systems Biology
Seattle, Washington, United States Recruiting
Study contacts
- Principal investigator: Jared C Roach, MD, PhD — Institute for Systems Biology
- Study coordinator: Jared C Roach, MD, PhD
- Email: caboom@isbscience.org
- Phone: 206-732-2108
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.